Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17945258 | 0.85 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL17945311 | 0.84 | ALDH1A1 (0.59) | KMT2AMEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL17945749 | 0.83 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL17945239 | 0.81 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL16613193 | 0.77 | ALDH1A1 (0.51) | KMT2AMEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL17945263 | 0.76 | MAPT (0.45) | KMT2AMEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL23814025 | 0.76 | ALDH1A1 (0.42) | KMT2AMEN1ATMALDH1A1MAPT | |
| SCHEMBL18079867 | 0.75 | ALDH1A1 (0.47) | KMT2AMEN1ATMALDH1A1HPGD | |
| SCHEMBL17945972 | 0.74 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL12957614 | 0.74 | HPGD (0.71) | KMT2AMEN1ATMALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160218301-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME | LG CHEM, LTD. (KR) | 2016-07-28 | — | — | US | disclosed |
| US-20160218301-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME | LG CHEM, LTD. (KR) | 2016-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160218301-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME | CRY1, CRY2, NR2E3 | KMT2A 326/4885MEN1 746/4885ATM 2709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.