Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 6/20 | 0.37 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 3/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.35 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.35 |
| ▸ | LAP3 | P28838 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19607556 | 0.90 | HIF1A (0.46) | HIF1ASLC7A5CA1CA2L3MBTL1 | |
| SCHEMBL23408418 | 0.81 | HIF1A (0.39) | HIF1ACA1CA2L3MBTL1ALDH1A1 | |
| SCHEMBL8112167 | 0.80 | CA1 (0.47) | HIF1ASLC7A5CA1CA2ANPEP | |
| SCHEMBL24983995 | 0.79 | HIF1A (0.42) | HIF1ACA1CA2ANPEPDNPEP | |
| SCHEMBL19559844 | 0.78 | SLC7A5 (0.56) | HIF1ASLC7A5ANPEPDNPEPRNPEP | |
| SCHEMBL8330499 | 0.78 | SLC7A5 (0.56) | HIF1ASLC7A5ANPEPDNPEPRNPEP | |
| SCHEMBL4677717 | 0.78 | SLC7A5 (0.56) | HIF1ASLC7A5ANPEPDNPEPRNPEP | |
| Hydrochloric Acid SCHEMBL27471876 | 0.78 | CA1 (0.45) | HIF1ASLC7A5CA1CA2ANPEP | |
| SCHEMBL19387754 | 0.78 | CA1 (0.55) | HIF1ACA1CA2L3MBTL1ALDH1A1 | |
| SCHEMBL14365019 | 0.77 | MMP9 (0.42) | SLC7A5RNPEPKISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106349156-B | It can be used as the pyridine -2- amides of CB2 agonist | 霍夫曼-拉罗奇有限公司 | 2018-12-11 | — | — | CN | disclosed |
| CN-106349156-A | Pyridine-2-amides capable of being used as CB2 agonist | 霍夫曼-拉罗奇有限公司 | 2017-01-25 | — | — | CN | disclosed |
| CN-103608332-B | Pyridine-2-amides useful as CB2 agonists | 霍夫曼-拉罗奇有限公司 | 2016-09-28 | — | — | CN | disclosed |
| US-20160215006-A1 | PEPTIDOMIMETIC INHIBITORS OF PSMA | WASHINGTON STATE UNIVERSITY (US) | 2016-07-28 | — | — | US | disclosed |
| CN-1148346-C | Hydrazine derivative | - | 2004-05-05 | — | — | CN | disclosed |
| CN-1309634-A | Hydrazine derivs. | HOFFMANN LA ROCHE (CH) | 2001-08-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160215006-A1 | PEPTIDOMIMETIC INHIBITORS OF PSMA | PSMA1, PSMA3, PSMA2 | HIF1A 511/4885SLC7A5 2393/4885CA1 124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.