Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 17/20 | 0.57 |
| ▸ | NPY1R | P25929 | 11/20 | 0.57 |
| ▸ | NPY5R | Q15761 | 10/20 | 0.57 |
| ▸ | NPY2R | P49146 | 7/20 | 0.57 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.49 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24306611 | 1.00 | NPY4R (0.57) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL27852310 | 0.95 | NPY4R (0.57) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL27852306 | 0.95 | NPY4R (0.57) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL12035313 | 0.94 | NPY4R (0.57) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL12035277 | 0.91 | NPY4R (0.55) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL14753920 | 0.91 | NPY4R (0.58) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL16045801 | 0.91 | SIRT5 (0.57) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL15987249 | 0.91 | SIRT5 (0.57) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL30688769 | 0.90 | ALDH1A1 (0.54) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL30688768 | 0.90 | ALDH1A1 (0.54) | NPY4RNPY1RNPY5RNPY2RKISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9453051-B2 | Cyclosporin derivatives | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2016-09-27 | — | — | US | disclosed |
| EP-2751127-B1 | CYCLOSPORIN DERIVATIVES | MAX PLANCK GES ZUR FÖRDERUNG DER WISSENSCHAFTEN E V (DE) | 2016-07-27 | — | — | EP | disclosed |