Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 7/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | RPS6KA2 | Q15349 | 2/20 | 0.36 |
| ▸ | RPS6KA1 | Q15418 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17952775 | 0.95 | HDAC6 (0.44) | RPS6KA3HDAC6SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL19270161 | 0.83 | HDAC6 (0.49) | HDAC6SMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17952908 | 0.80 | SMN1; SMN2 (0.42) | HDAC6SMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17952925 | 0.79 | RPS6KA3 (0.40) | RPS6KA3SMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17952917 | 0.79 | HPGD (0.41) | RPS6KA3SMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL15470447 | 0.79 | HDAC6 (0.57) | HDAC6L3MBTL1MAOAACHE | |
| SCHEMBL21693361 | 0.78 | CYP1A2 (0.47) | HDAC6SMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17952723 | 0.78 | SMN1; SMN2 (0.45) | HDAC6SMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17952784 | 0.78 | RPS6KA3 (0.41) | RPS6KA3SMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17952893 | 0.77 | RPS6KA3 (0.38) | RPS6KA3CYP1A2CYP3A4CYP2D6RPS6KA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3247771-B1 | PYRIDINES AND DERIVATIVES THEREOF AS COMPONENTS FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2020-06-10 | — | — | EP | disclosed |
| US-10544361-B2 | Pyridines and derivatives thereof as components for use in optoelectronic components | CYNORA GMBH (DE) | 2020-01-28 | — | — | US | disclosed |
| WO-2016116517-A1 | PYRIDINES AND DERIVATIVES THEREOF AS COMPONENTS FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2016-07-28 | — | — | WO | disclosed |