Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21693361 | 0.88 | CYP1A2 (0.47) | SMN1; SMN2CYP1A2CYP3A4CYP2D6MAOA | |
| SCHEMBL17952723 | 0.88 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP1A2CYP3A4CYP2D6MAOA | |
| SCHEMBL21928129 | 0.84 | FNTA (0.40) | SMN1; SMN2CYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL21928130 | 0.84 | UCHL1 (0.39) | SMN1; SMN2CYP1A2CYP3A4CYP2D6MAOA | |
| SCHEMBL21921751 | 0.83 | FNTA (0.40) | SMN1; SMN2CYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL21927712 | 0.83 | UCHL1 (0.39) | SMN1; SMN2CYP1A2CYP3A4CYP2D6MAOA | |
| SCHEMBL17952775 | 0.81 | HDAC6 (0.44) | SMN1; SMN2CYP1A2CYP3A4CYP2D6MAOA | |
| SCHEMBL17952926 | 0.80 | RPS6KA3 (0.44) | SMN1; SMN2CYP1A2CYP3A4CYP2D6MAOA | |
| SCHEMBL17952929 | 0.79 | MAOA (0.42) | SMN1; SMN2CYP1A2CYP2D6MAOAMAOB | |
| SCHEMBL21928514 | 0.78 | PDE10A (0.39) | SMN1; SMN2CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3247771-B1 | PYRIDINES AND DERIVATIVES THEREOF AS COMPONENTS FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2020-06-10 | — | — | EP | disclosed |
| US-10544361-B2 | Pyridines and derivatives thereof as components for use in optoelectronic components | CYNORA GMBH (DE) | 2020-01-28 | — | — | US | disclosed |
| WO-2016116517-A1 | PYRIDINES AND DERIVATIVES THEREOF AS COMPONENTS FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2016-07-28 | — | — | WO | disclosed |