Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 9/20 | 0.40 |
| ▸ | RPS6KA2 | Q15349 | 2/20 | 0.36 |
| ▸ | RPS6KA1 | Q15418 | 2/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17952784 | 0.95 | RPS6KA3 (0.41) | RPS6KA3RPS6KA2RPS6KA1CDK8MAOA | |
| SCHEMBL19268478 | 0.83 | NOTUM (0.42) | CDK8CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL17952929 | 0.81 | MAOA (0.42) | CDK8MAOAMAOBCYP1A2CYP2D6 | |
| SCHEMBL17952893 | 0.80 | RPS6KA3 (0.38) | RPS6KA3RPS6KA2RPS6KA1MAOAMAOB | |
| SCHEMBL17952917 | 0.79 | HPGD (0.41) | RPS6KA3RPS6KA2RPS6KA1MAOAMAOB | |
| SCHEMBL17952926 | 0.79 | RPS6KA3 (0.44) | RPS6KA3RPS6KA2RPS6KA1MAOACYP46A1 | |
| SCHEMBL27967964 | 0.79 | CDK8 (0.43) | CDK8MAOAMAOBCYP1A2CYP3A4 | |
| SCHEMBL6123854 | 0.79 | P2RX4 (0.42) | SMN1; SMN2P2RX4 | |
| SCHEMBL20308279 | 0.78 | ALDH1A1 (0.38) | CDK8CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL17952722 | 0.78 | P2RX4 (0.37) | CDK8MAOAMAOBCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3247771-B1 | PYRIDINES AND DERIVATIVES THEREOF AS COMPONENTS FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2020-06-10 | — | — | EP | disclosed |
| US-10544361-B2 | Pyridines and derivatives thereof as components for use in optoelectronic components | CYNORA GMBH (DE) | 2020-01-28 | — | — | US | disclosed |
| WO-2016116517-A1 | PYRIDINES AND DERIVATIVES THEREOF AS COMPONENTS FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2016-07-28 | — | — | WO | disclosed |