SCHEMBL1795374

SCHEMBL1795374

O=C(O)c1ccc(CI)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.60
TSHR P16473 3/20 0.60
TP53 P04637 1/20 0.60
TPMT P51580 1/20 0.54
SRD5A2 P31213 3/20 0.52
KMT2A Q03164 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA12 O43570 1/20 0.50
CA3 P07451 1/20 0.50
TYR P14679 1/20 0.50
DRD1 P21728 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
RXRA P19793 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL1596492 0.98 ALDH1A1 (0.58) ALDH1A1TSHRTP53TPMTSRD5A2
Hydrochloric Acid SCHEMBL1596308 0.98 ALDH1A1 (0.58) ALDH1A1TSHRTP53TPMTSRD5A2
SCHEMBL27686225 0.93 ALDH1A1 (0.54) ALDH1A1TSHRTP53TPMTSRD5A2
SCHEMBL13660529 0.88 ALDH1A1 (0.59) ALDH1A1TSHRTP53RXRARXRB
SCHEMBL1541438 0.83 ALDH1A1 (0.58) ALDH1A1TSHRTP53TPMTSRD5A2
SCHEMBL19156918 0.82 KMT2A (0.41) ALDH1A1TSHRTP53KMT2ACA1
SCHEMBL423964 0.82 TSHR (0.63) ALDH1A1TSHRTP53TPMTSRD5A2
SCHEMBL1596491 0.80 GSK3B (0.41) ALDH1A1KMT2ACA1CA2MEN1
SCHEMBL7408277 0.79 ALDH1A1 (0.61) ALDH1A1SRD5A2KMT2ASMN1; SMN2MEN1
Terephthalic Acid SCHEMBL4612225 0.79 TSHR (0.67) ALDH1A1TSHRTP53TPMTSRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119978361-A Lignin grafted polyoxazoline copolymer and preparation method thereof 合肥工业大学 2025-05-13 CN claimed
CN-114989426-B Polymer brush of poly (isonitrile) grafted polyoxazoline and preparation method thereof 合肥工业大学 2024-03-15 CN claimed
CN-116768723-A Tevaleraldehyde remote polyarylation method 常州大学 2023-09-19 CN claimed
CN-114989426-A Polymer brush of polyisonitrile grafted polyoxazoline and preparation method thereof 合肥工业大学 2022-09-02 CN claimed
CN-109574811-B Preparation method of anidulafungin side chain intermediate p-pentoxy terphenyl formic acid 中山大学 2021-12-24 CN claimed
CN-113620878-A Ni metal-organic framework material and preparation method and application thereof 山西大学 2021-11-09 CN claimed
CN-109053349-B Synthesis method of biaryl compound catalyzed by palladium/sensory components 河南农业大学 2021-08-03 CN claimed
CN-109776504-B Metal organic framework material based on low-symmetry pyrazole-carboxylic acid ligand Zn, and preparation method and application thereof 北京工业大学 2020-10-16 CN claimed
CN-109212056-A The gas chromatography-mass spectrometry of three kinds of trace monohaloalkyl methyl benzoic acids in a kind of measurement source water 丁立平 2019-01-15 CN claimed
CN-108863894-A A kind of method of the direct synthesis of indole of nitrile 中国科学技术大学 2018-11-23 CN claimed
CN-100516862-C Capillary electrophoresis uantitative analytical method for impurities content in refined p-phthalic acid SHANGHAI INST ORGANIC CHEM (CN) 2009-07-22 CN claimed
CN-1908646-A Capillary electrophoresis uantitative analytical method for impurities content in refined p-phthalic acid SHANGHAI INST ORGANIC CHEM (CN) 2007-02-07 CN claimed
CN-119978361-A Lignin grafted polyoxazoline copolymer and preparation method thereof 合肥工业大学 2025-05-13 CN disclosed
CN-118084670-A Preparation method of iodo aromatic hydrocarbon 黑龙江立科新材料有限公司 2024-05-28 CN disclosed
CN-114989426-B Polymer brush of poly (isonitrile) grafted polyoxazoline and preparation method thereof 合肥工业大学 2024-03-15 CN disclosed
US-20230372358-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING A RYANODINE RECEPTOR MODULATOR AND USES THEREOF RYCARMA THERAPEUTICS, INC. 2023-11-23 US disclosed
EP-0512675-A1 Angiotensin II antagonists incorporating a substituted thiophene or furan MERCK & CO. INC. (US) 1992-11-11 EP disclosed
EP-0510812-A1 Angiotensin II antagonists incorporating a substituted thiophene or furan MERCK & CO. INC. (US) 1992-10-28 EP disclosed
US-4469865-A INHIBITORS OF THROMBOXANE SYNTHETASE KISSEI PHARMACEUTICAL CO., LTD. (JP) 1984-09-04 US disclosed
EP-0076140-A2 1,3-Disubstituted imidazoles and a process for their production Kissei Pharmaceutical Co. Ltd. (JP) 1983-04-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230372358-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING A RYANODINE RECEPTOR MODULATOR AND USES THEREOF RYR1, RYR2, MUSK ALDH1A1 1707/4885TSHR 1484/4885TP53 762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.