SCHEMBL1596491

SCHEMBL1596491

O=C(Br)c1ccc(CI)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.41
KMT2A Q03164 2/20 0.39
HDAC6 Q9UBN7 3/20 0.39
PLK1 P53350 2/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
HDAC3 O15379 1/20 0.39
NCOR2 Q9Y618 1/20 0.39
ALDH1A1 P00352 1/20 0.38
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
OGG1 O15527 1/20 0.37
HDAC1 Q13547 2/20 0.36
POLB P06746 1/20 0.36
CTDSP1 Q9GZU7 1/20 0.36
PLA2G10 O15496 1/20 0.34
PLA2G2A P14555 1/20 0.34
LMNA P02545 1/20 0.34
MEN1 O00255 1/20 0.34
HDAC8 Q9BY41 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19156918 0.82 KMT2A (0.41) GSK3BKMT2AHDAC6PLK1CES2
SCHEMBL688186 0.81 TP53 (0.47) KMT2AHDAC6PLK1CES2CES1
SCHEMBL1795374 0.80 ALDH1A1 (0.60) KMT2AALDH1A1CA1CA2POLB
SCHEMBL1290706 0.79 KMT2A (0.61) KMT2AHDAC6PLK1CES2CES1
SCHEMBL14346127 0.78 KMT2A (0.67) KMT2AALDH1A1LMNA
SCHEMBL27896185 0.78 PLA2G10 (0.57) KMT2AALDH1A1CA1CA2POLB
Hydrochloric Acid SCHEMBL1596308 0.78 ALDH1A1 (0.58) KMT2AALDH1A1CA1CA2POLB
SCHEMBL1596305 0.78 ALDH1A1 (0.43) GSK3BKMT2AHDAC6PLK1CES2
Bromide SCHEMBL1596492 0.78 ALDH1A1 (0.58) KMT2AALDH1A1CA1CA2POLB
SCHEMBL14101271 0.78 PLK1 (0.68) KMT2AHDAC6PLK1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119798229-A Preparation method of imatinib dimer 中国食品药品检定研究院 2025-04-11 CN claimed
CN-119798229-A Preparation method of imatinib dimer 中国食品药品检定研究院 2025-04-11 CN disclosed
EP-1780224-B1 MULTIBRANCHED POLYMERS AND PROCESS FOR PRODUCTION THEREOF NIPPON SODA CO (JP) 2015-02-18 EP disclosed
US-8710165-B2 Multibranched polymer and method for producing the same NIPPON SODA CO., LTD. (JP) 2014-04-29 US disclosed
CN-101001887-B Multi-branched polymer and method for producing same NIPPON SODA CO.,LTD. (JP) 2012-02-08 CN disclosed
US-20110152388-A1 Multibranched polymer and method for producing the same NIPPON SODA CO., LTD. (JP) 2011-06-23 US disclosed
US-7919570-B2 narrowly dispersed; controlled molecular weight; ionic conductivity, shape stability; battery adhesive or binder; 1,1,2,2-tetrakis(4-hydroxyphenyl)ethane or pentaerythritol reacted with bromoisobutyroyl bromide for core; living radical polymerization of acrylate or a styrene at halogen atoms as the arms NIPPON SODA CO., LTD. (JP) 2011-04-05 US disclosed
CN-101593852-B Multibranched polymers and process for production thereof NIPPON SODA CO 2011-03-02 CN disclosed
CN-101593852-A Multibranched polymers and manufacture method thereof NIPPON SODA CO (JP) 2009-12-02 CN disclosed
US-20080214685-A1 Multibrached Polymer and Method for Producing the Same NIPPON SODA CO., LTD. (JP) 2008-09-04 US disclosed
CN-101001887-A Multi-branched polymer and method for producing same NIPPON SODA CO (JP) 2007-07-18 CN disclosed
EP-1780224-A1 MULTIBRANCHED POLYMERS AND PROCESS FOR PRODUCTION THEREOF NIPPON SODA CO., LTD. (JP) 2007-05-02 EP disclosed