Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 2/20 | 0.60 |
| ▸ | FAAH | O00519 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16599328 | 0.85 | LMNA (0.64) | GRIN2BFAAHMEN1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL6584348 | 0.79 | GRIN2B (0.88) | GRIN2BMEN1KMT2ATSHRHSD17B10 | |
| SCHEMBL1134958 | 0.78 | GRIN2B (0.75) | GRIN2BFAAHMEN1KMT2ATSHR | |
| SCHEMBL17954131 | 0.75 | FAAH (0.48) | FAAHMEN1KMT2AACACBSMN1; SMN2 | |
| SCHEMBL3601029 | 0.74 | FAAH (1.00) | FAAHTSHRMAPTRAB9AKDM4E | |
| SCHEMBL17954126 | 0.74 | MAPK14 (0.66) | FAAHKMT2ALMNAMAPTACACB | |
| SCHEMBL17954124 | 0.72 | GRIN2B (0.62) | GRIN2BFAAHMEN1KMT2AHSD17B10 | |
| Hydrochloric Acid SCHEMBL10334450 | 0.72 | GRIN2B (0.62) | GRIN2BMEN1KMT2ATSHRHSD17B10 | |
| SCHEMBL8061129 | 0.71 | TSHR (0.70) | GRIN2BMEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL12227071 | 0.71 | FAAH (0.58) | FAAHMEN1KMT2ASSTR5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9776979-B2 | EBI2 modulators | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2017-10-03 | — | — | US | disclosed |
| US-20160214951-A1 | EBI2 MODULATORS | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE | 2016-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160214951-A1 | EBI2 MODULATORS | BIRC2, HAVCR2, MAVS | GRIN2B 1194/4885FAAH 3473/4885MEN1 2201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.