Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1795608 | 1.00 | VCAM1 (0.51) | VCAM1MAPTKMT2APDK1KAT2B | |
| SCHEMBL2793480 | 0.85 | VCAM1 (0.54) | VCAM1MAPTKMT2APDK1KAT2B | |
| SCHEMBL2793482 | 0.85 | VCAM1 (0.54) | VCAM1MAPTKMT2APDK1KAT2B | |
| SCHEMBL22898036 | 0.84 | VCAM1 (0.55) | VCAM1MAPTKMT2APDK1KAT2B | |
| SCHEMBL25492000 | 0.83 | VCAM1 (0.58) | VCAM1MAPTKMT2APDK1KAT2B | |
| SCHEMBL6217577 | 0.83 | VCAM1 (0.51) | VCAM1MAPTKMT2APDK1KAT2B | |
| SCHEMBL6217572 | 0.83 | VCAM1 (0.51) | VCAM1MAPTKMT2APDK1KAT2B | |
| SCHEMBL7965821 | 0.82 | VCAM1 (0.48) | VCAM1MAPTKMT2APDK1KAT2B | |
| SCHEMBL7965816 | 0.82 | VCAM1 (0.48) | VCAM1MAPTKMT2APDK1KAT2B | |
| SCHEMBL28949567 | 0.81 | VCAM1 (0.55) | VCAM1MAPTKMT2APDK1KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951825-B2 | Hetero compound | ASTELLAS PHARMA INC. (JP) | 2011-05-31 | — | — | US | disclosed |