Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 4/20 | 0.58 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.50 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MERTK | Q12866 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28949567 | 0.87 | VCAM1 (0.55) | VCAM1PDK1KAT2BMAPTKMT2A | |
| SCHEMBL22898036 | 0.87 | VCAM1 (0.55) | VCAM1PDK1KAT2BMAPTKMT2A | |
| SCHEMBL22897766 | 0.84 | VCAM1 (0.53) | VCAM1PDK1KAT2BMAPTKMT2A | |
| SCHEMBL16957674 | 0.83 | PDK1 (0.50) | VCAM1PDK1MAPTMAPK1TDP1 | |
| SCHEMBL11229564 | 0.83 | PDK1 (0.50) | VCAM1PDK1MAPTMAPK1TDP1 | |
| SCHEMBL1795604 | 0.83 | VCAM1 (0.51) | VCAM1PDK1KAT2BMAPTKMT2A | |
| SCHEMBL1795608 | 0.83 | VCAM1 (0.51) | VCAM1PDK1KAT2BMAPTKMT2A | |
| SCHEMBL2793482 | 0.80 | VCAM1 (0.54) | VCAM1PDK1KAT2BMAPTKMT2A | |
| SCHEMBL2793480 | 0.80 | VCAM1 (0.54) | VCAM1PDK1KAT2BMAPTKMT2A | |
| SCHEMBL1795775 | 0.79 | ALDH1A1 (0.61) | VCAM1PDK1KAT2BMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11655244-B2 | Carbazole compounds and methods of use thereof | GSNO THERAPEUTICS, INC. (US) | 2023-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11655244-B2 | Carbazole compounds and methods of use thereof | GSR, CBR3, CBR1 | VCAM1 3419/4885PDK1 1664/4885KAT2B 2028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.