SCHEMBL1796352

SCHEMBL1796352

CCCCCCCN=C(N)N

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
DHPS P49366 1/20 0.61
PRSS1 P07477 1/20 0.59
PRSS2 P07478 1/20 0.59
PRSS3 P35030 1/20 0.59
CYP1A2 P05177 2/20 0.56
ALOX15 P16050 1/20 0.56
NFKB1 P19838 1/20 0.56
MAOA P21397 1/20 0.56
MAOB P27338 1/20 0.56
LMNA P02545 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5306840 1.00 MEN1 (1.00) MEN1KMT2ADHPSPRSS1PRSS2
SCHEMBL1249219 1.00 MEN1 (1.00) MEN1KMT2ADHPSPRSS1PRSS2
SCHEMBL5597193 1.00 MEN1 (1.00) MEN1KMT2ADHPSPRSS1PRSS2
SCHEMBL4104867 1.00 MEN1 (1.00) MEN1KMT2ADHPSPRSS1PRSS2
SCHEMBL5812638 1.00 MEN1 (1.00) MEN1KMT2ADHPSPRSS1PRSS2
SCHEMBL5300899 1.00 MEN1 (1.00) MEN1KMT2ADHPSPRSS1PRSS2
SCHEMBL1138747 1.00 MEN1 (1.00) MEN1KMT2ADHPSPRSS1PRSS2
SCHEMBL261682 1.00 MEN1 (1.00) MEN1KMT2ADHPSPRSS1PRSS2
SCHEMBL1069234 1.00 MEN1 (1.00) MEN1KMT2ADHPSPRSS1PRSS2
SCHEMBL8752675 1.00 MEN1 (1.00) MEN1KMT2ADHPSPRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112048083-B Preparation method of guanidino-containing antibacterial polymer for promoting diabetic ulcer skin repair 宁波大学 2022-12-16 CN claimed
CN-108117505-A A kind of preparation method for synthesizing diphenyl ether imidodicarbonic diamide 杜庶铭 2018-06-05 CN claimed
CN-112048083-B Preparation method of guanidino-containing antibacterial polymer for promoting diabetic ulcer skin repair 宁波大学 2022-12-16 CN disclosed
CN-112048083-A Antimicrobial polymer containing guanidino for promoting diabetic ulcer skin repair and preparation method thereof 宁波大学 2020-12-08 CN disclosed
CN-105339340-B Generated base alkaline agent, the alkali reactive composition containing the generated base alkaline agent and production alkali method 富士胶片和光纯药株式会社 2018-10-12 CN disclosed
CN-106414461-B Borate-based generated base alkaline agent and alkali reactive composition containing the generated base alkaline agent 富士胶片和光纯药株式会社 2018-09-11 CN disclosed
CN-108117505-A A kind of preparation method for synthesizing diphenyl ether imidodicarbonic diamide 杜庶铭 2018-06-05 CN disclosed
CN-107848963-A Alkali-producing agent and/or radical-generating agent having acid resistance, and curable resin composition containing same 和光纯药工业株式会社 2018-03-27 CN disclosed
CN-106414461-A BORATE-BASED BASE GENERATOR, AND BASE-REACTIVE COMPOSITION COMPRISING SUCH BASE GENERATOR 和光纯药工业株式会社 2017-02-15 CN disclosed
CN-105339340-A Base generator, base-reactive composition containing said base generator, and base generation method WAKO PURE CHEM IND LTD 2016-02-17 CN disclosed
US-8871210-B2 Chemokine receptor antagonists and use thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2014-10-28 US disclosed
EP-2055705-A1 COMPOUND HAVING CYCLIC GROUP BOUND THERETO THROUGH SPIRO BINDING AND USE THEREOF Ono Pharmaceutical CO., LTD. (JP) 2009-05-06 EP disclosed
EP-2042503-A1 COMPOUND HAVING ACIDIC GROUP WHICH MAY BE PROTECTED, AND USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2009-04-01 EP disclosed
EP-1961744-A1 BASIC GROUP-CONTAINING COMPOUND AND USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2008-08-27 EP disclosed
EP-1942108-A1 COMPOUND CONTAINING BASIC GROUP AND USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2008-07-09 EP disclosed
US-20080009495-A1 Compound Containing Basic Group and Use Thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2008-01-10 US disclosed
EP-1852432-A1 NITROGENOUS HETEROCYCLIC COMPOUND AND MEDICINAL USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2007-11-07 EP disclosed
EP-1790639-A1 COMPOUND CONTAINING BASIC GROUP AND USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2007-05-30 EP disclosed
EP-1080091-A1 NOVEL 1,3,8-TRIAZASPIRO[4.5]DECANONES WITH HIGH AFFINITY FOR OPIOID RECEPTOR SUBTYPES Novo Nordisk A/S (DK) 2001-03-07 EP disclosed
WO-1999059997-A1 NOVEL 1,3,8-TRIAZASPIRO[4.5]DECANONES WITH HIGH AFFINITY FOR OPIOID RECEPTOR SUBTYPES NOVO NORDISK A/S (DK) 1999-11-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080009495-A1 Compound Containing Basic Group and Use Thereof CXCR4, CCR5, CXCR3 MEN1 2163/4885KMT2A 3544/4885DHPS 1701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.