Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KLK1 | P06870 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1057982 | 0.81 | SMN1; SMN2 (0.35) | SMN1; SMN2HTR7LMNAMAPTMAPK1 | |
| SCHEMBL9957027 | 0.79 | ALDH1A1 (0.46) | SMN1; SMN2HTR7LMNAMAPTMAPK1 | |
| SCHEMBL21991382 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2HTR7LMNAMAPTMAPK1 | |
| SCHEMBL4483072 | 0.79 | TAAR1 (0.46) | SMN1; SMN2MAPK1HPGDKLK1RAB9A | |
| SCHEMBL20482100 | 0.79 | SMN1; SMN2 (0.39) | SMN1; SMN2HTR7LMNAMAPTMAPK1 | |
| SCHEMBL4953222 | 0.77 | KLK1 (0.43) | SMN1; SMN2HTR7LMNAMAPTMAPK1 | |
| SCHEMBL12646924 | 0.77 | THRA (0.50) | SMN1; SMN2LMNAMAPTMAPK1L3MBTL1 | |
| SCHEMBL1929353 | 0.77 | HTR7 (0.58) | SMN1; SMN2HTR7LMNAMAPTMAPK1 | |
| SCHEMBL28912859 | 0.77 | MRGPRX4 (0.47) | SMN1; SMN2HTR7LMNAMAPTMAPK1 | |
| SCHEMBL21899044 | 0.76 | KMT2A (0.50) | SMN1; SMN2LMNAMAPTMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951799-B2 | sugar transport enhancement agent; antidiabetic and hypoglycemic agent; obesity, diabetic nephropathy, retinopathy, macrovascular disease, glucose tolerance anomaly; cyclization of 4-(2-aminocyclohexylamino)-3-pyrroline-2-one by aldehyde followed by acylation | AJINOMOTO CO., INC. (JP) | 2011-05-31 | — | — | US | disclosed |
| US-20080108604-A1 | NOVEL LACTAM COMPOUND | AJINOMOTO CO., INC. (JP) | 2008-05-08 | — | — | US | disclosed |
| EP-1878734-A1 | NOVEL LACTAM COMPOUND | Ajinomoto Co., Inc. (JP) | 2008-01-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108604-A1 | NOVEL LACTAM COMPOUND | SLC2A4, SLC2A1, SLC2A9 | SMN1; SMN2 1021/4885HTR7 4625/4885LMNA 3522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.