Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 6/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.35 |
| ▸ | SKP1 | P63208 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17965166 | 0.88 | S1PR1 (0.49) | S1PR1S1PR3HDAC3HDAC1HDAC2 | |
| SCHEMBL17964993 | 0.86 | TLR9 (0.43) | KMT2ALMNAS1PR1S1PR3HDAC3 | |
| SCHEMBL17965084 | 0.85 | EGLN1 (0.43) | KMT2ALMNAS1PR1S1PR3HDAC3 | |
| SCHEMBL14242759 | 0.79 | P2RY14 (0.53) | CETPP2RY14 | |
| SCHEMBL17965106 | 0.77 | LMNA (0.40) | LMNAS1PR1S1PR3HDAC3HDAC1 | |
| SCHEMBL17964995 | 0.75 | S1PR1 (0.48) | S1PR1S1PR3HDAC3HDAC1HDAC2 | |
| SCHEMBL17965196 | 0.73 | S1PR1 (0.45) | S1PR1S1PR3HDAC3HDAC1HDAC2 | |
| SCHEMBL15732487 | 0.72 | RPS6KB1 (0.42) | P2RY14 | |
| SCHEMBL17965095 | 0.72 | S1PR1 (0.56) | S1PR1S1PR3HDAC3HDAC1HDAC2 | |
| SCHEMBL4466566 | 0.72 | KMO (0.38) | HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718279-B1 | NOVEL COMPOUNDS AS MODULATORS OF GPR-119 | RHIZEN PHARMACEUTICALS SA (CH) | 2016-08-10 | — | — | EP | claimed |