Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.74 |
| ▸ | APP | P05067 | 5/20 | 0.59 |
| ▸ | SNCA | P37840 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17968556 | 1.00 | ENPP2 (0.74) | ENPP2APPSNCAKMT2ACNR1 | |
| SCHEMBL17968561 | 0.85 | ENPP2 (1.00) | ENPP2APPSNCAKMT2AMEN1 | |
| SCHEMBL17968559 | 0.85 | ENPP2 (1.00) | ENPP2APPSNCAKMT2AMEN1 | |
| SCHEMBL24164296 | 0.84 | APP (0.64) | ENPP2APPSNCAKMT2ACNR1 | |
| SCHEMBL17958368 | 0.84 | APP (0.72) | ENPP2APPSNCAKMT2AMEN1 | |
| SCHEMBL16596318 | 0.84 | APP (0.72) | ENPP2APPSNCAKMT2AMEN1 | |
| SCHEMBL17968565 | 0.84 | ENPP2 (1.00) | ENPP2APPSNCAKMT2AMEN1 | |
| SCHEMBL17968563 | 0.84 | ENPP2 (1.00) | ENPP2APPSNCAKMT2AMEN1 | |
| SCHEMBL17958293 | 0.82 | ENPP2 (0.67) | ENPP2APPSNCAKMT2AMEN1 | |
| SCHEMBL16596378 | 0.82 | ENPP2 (0.67) | ENPP2APPSNCAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951026-B2 | Heterocyclic vinyl autotaxin inhibitor compounds | PHARMAKEA, INC. (US) | 2018-04-24 | — | — | US | disclosed |
| US-20160229809-A1 | HETEROCYCLIC VINYL AUTOTAXIN INHIBITOR COMPOUNDS | DF 2024 IP ACQUISITION, LLC | 2016-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160229809-A1 | HETEROCYCLIC VINYL AUTOTAXIN INHIBITOR COMPOUNDS | ENPP2, SERPINB1, UACA | ENPP2 1/4885APP 1280/4885SNCA 2428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.