SCHEMBL17969781

SCHEMBL17969781

CCOC(=O)C1=C(c2ccccc2)C(=O)c2ccccc2C1=O

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.78
LMNA P02545 6/20 0.78
NPSR1 Q6W5P4 6/20 0.78
MAPT P10636 6/20 0.78
MEN1 O00255 5/20 0.78
KMT2A Q03164 5/20 0.78
HKDC1 Q2TB90 5/20 0.78
KDM4E B2RXH2 4/20 0.78
HSP90AA1 P07900 3/20 0.78
SMN1; SMN2 Q16637 3/20 0.78
HTT P42858 3/20 0.78
TDP1 Q9NUW8 3/20 0.78
L3MBTL1 Q9Y468 2/20 0.78
NPC1 O15118 1/20 0.78
TP53 P04637 1/20 0.78
MAPK1 P28482 1/20 0.78
MPI P34949 1/20 0.78
RAB9A P51151 1/20 0.78
PPARG P37231 4/20 0.64
HSP90AB1 P08238 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7538581 0.94 PPARG (0.72) ALDH1A1LMNANPSR1MAPTMEN1
SCHEMBL9904567 0.91 MAPT (0.78) ALDH1A1LMNANPSR1MAPTMEN1
SCHEMBL13561203 0.89 HSP90AA1 (0.74) ALDH1A1LMNANPSR1MAPTMEN1
SCHEMBL2489785 0.88 MAPT (1.00) ALDH1A1LMNANPSR1MAPTMEN1
SCHEMBL8359086 0.87 PPARG (0.63) ALDH1A1LMNANPSR1MAPTMEN1
SCHEMBL8340214 0.84 MAPT (0.56) ALDH1A1LMNANPSR1MAPTMEN1
SCHEMBL445362 0.84 ALDH1A1 (0.56) ALDH1A1LMNANPSR1MAPTMEN1
SCHEMBL13679127 0.84 NPSR1 (0.56) ALDH1A1LMNANPSR1MAPTMEN1
SCHEMBL15827661 0.84 NPSR1 (0.56) ALDH1A1LMNANPSR1MAPTMEN1
SCHEMBL17969780 0.83 FGFR1 (0.88) ALDH1A1LMNANPSR1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9760029-B2 Electrophotographic photosensitive member, image forming apparatus, and process cartridge KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-09-12 US disclosed
US-9760029-B2 Electrophotographic photosensitive member, image forming apparatus, and process cartridge KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-09-12 US disclosed
US-20160223923-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2016-08-04 US disclosed
US-20160223923-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2016-08-04 US disclosed
EP-3051352-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER AND METHOD FOR MANUFACTURING THE SAME, AND IMAGE FORMING APPARATUS Kyocera Document Solutions Inc. (JP) 2016-08-03 EP disclosed