Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL179727

CCCCCCCCCCCCCCCCC(CCCCCCCCCCCCCCCC)=C(CCCCCCCCCCCCCCCC)CCCCCCCCCCCCCCCC.N.N

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.55
CES1 P23141 4/20 0.55
TSHR P16473 5/20 0.53
THRB P10828 1/20 0.53
GPR84 Q9NQS5 7/20 0.52
PPARG P37231 7/20 0.52
PPARD Q03181 7/20 0.52
PPARA Q07869 7/20 0.52
HDAC11 Q96DB2 5/20 0.52
PTPN1 P18031 3/20 0.52
ALDH1A1 P00352 2/20 0.52
TLR2 O60603 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
FABP4 P15090 2/20 0.52
SLC22A6 Q4U2R8 1/20 0.52
SLC22A8 Q8TCC7 1/20 0.52
MEN1 O00255 1/20 0.52
ESR1 P03372 1/20 0.52
ALOX15 P16050 1/20 0.52
PDE4A P27815 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL11778398 1.00 CES2 (0.55) CES2CES1TSHRTHRBGPR84
Ammonia Solution, Strong SCHEMBL20801523 1.00 CES2 (0.55) CES2CES1TSHRTHRBGPR84
Ammonia Solution, Strong SCHEMBL6861504 0.97 CES2 (0.52) CES2CES1TSHRTHRBGPR84
SCHEMBL1527621 0.97 CES2 (0.58) CES2CES1TSHRTHRBGPR84
SCHEMBL11239831 0.97 CES2 (0.58) CES2CES1TSHRTHRBGPR84
SCHEMBL5689910 0.97 CES2 (0.58) CES2CES1TSHRTHRBGPR84
SCHEMBL10349515 0.93 CES2 (0.55) CES2CES1TSHRTHRBGPR84
SCHEMBL3401724 0.93 CES2 (0.56) CES2CES1TSHRTHRBGPR84
SCHEMBL28958962 0.90 CES2 (0.52) CES2CES1TSHRTHRBGPR84
Ammonia Solution, Strong SCHEMBL4627589 0.86 CES1 (0.50) CES2CES1TSHRTHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 522 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9217128-B2 Composition including one or more hydrolytically unstable components CHEMLINK SPECIALITIES LTD (GB) 2015-12-22 US claimed
EP-2014756-B1 Laundry multi-compartment pouch composition PROCTER & GAMBLE (US) 2011-03-30 EP claimed
EP-1682647-B1 COMPOSITION INCLUDING ONE OR MORE HYDROLYTICALLY UNSTABLE COMPONENTS CHEMLINK SPECIALITIES LTD (GB) 2007-08-01 EP claimed
US-20070129277-A1 Composition including one or more hydrolytically unstable components SOLUPAK LTD (GB) 2007-06-07 US claimed
EP-1682647-A1 COMPOSITION INCLUDING ONE OR MORE HYDROLYTICALLY UNSTABLE COMPONENTS Chemlink Specialities Ltd. (GB) 2006-07-26 EP claimed
WO-2005052108-A1 COMPOSITION INCLUDING ONE OR MORE HYDROLYTICALLY UNSTABLE COMPONENTS CHEMLINK SPECIALITIES LTD (GB) 2005-06-09 WO claimed
EP-0692020-B1 STABLE, BIFUNCTIONAL, PHOSPHATE-, METASILICATE- AND POLYMER-FREE LOW ALKALINE DETERGENT TABLETS FOR DISHWASHING MACHINES, AND PROCESS FOR PRODUCING THE SAME HENKEL KGAA (DE) 1997-11-12 EP claimed
EP-0037026-B1 PROCESS FOR THE PREPARATION OF A STORAGE-STABLE, EASILY SOLUBLE GRANULATED COMPOUND CONTAINING A BLEACH ACTIVATOR Henkel Kommanditgesellschaft auf Aktien (DE) 1985-07-31 EP claimed
EP-0070432-B1 PROCESS FOR THE PREPARATION OF PURIFIED TETRAACETYLETHYLENE DIAMINE (TAED) BAYER AG (DE) 1985-04-03 EP claimed
JP-3053000-A None JP disclosed
US-12630812-B2 Subtilase variants and polynucleotides encoding same NOVOZYMES A/S (DK) 2026-05-19 US disclosed
EP-4739760-A1 WASHING METHOD FOR REMOVING PROTEINACEOUS STAINS Novozymes A/S (DK) 2026-05-13 EP disclosed
US-12606810-B2 Subtilase variants and compositions comprising same NOVOZYMES A/S (DK) 2026-04-21 US disclosed
US-12529016-B2 Subtilase variants NOVOZYMES A/S (DK) 2026-01-20 US disclosed
US-4681695-A SPRAY DRIED ACTIVATOR THE PROCTER & GAMBLE COMPANY (US) 1987-07-21 US disclosed
EP-0174132-A2 Bleach activator compositions manufacture and use thereof in laundry compositions THE PROCTER & GAMBLE COMPANY (US) 1986-03-12 EP disclosed
EP-0051508-B1 BLEACHING COMPOSITIONS L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 1984-10-24 EP disclosed
EP-0079671-A3 PROCESS FOR PREPARING TETRAACETYL ALKYLENE DIAMINES Albright & Wilson Limited (GB) 1984-03-21 EP disclosed
EP-0079671-A2 Process for preparing tetraacetyl alkylene diamines Albright & Wilson Limited (GB) 1983-05-25 EP disclosed
EP-0051508-A1 Bleaching compositions L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 1982-05-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12529016-B2 Subtilase variants PEPD, DPP9, TMPRSS15 CES2 1112/4885CES1 258/4885TSHR 3452/4885
US-12606810-B2 Subtilase variants and compositions comprising same PRSS1, CTRL, TMPRSS11D CES2 2418/4885CES1 333/4885TSHR 1255/4885
US-12630812-B2 Subtilase variants and polynucleotides encoding same RNASE1, PEPD, DPP9 CES2 2337/4885CES1 994/4885TSHR 2897/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.