Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 9/20 | 0.50 |
| ▸ | CNR2 | P34972 | 9/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.42 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1800176 | 1.00 | SERPINE1 (0.51) | SERPINE1CNR1CNR2KDM4ETSHR | |
| SCHEMBL1797272 | 1.00 | SERPINE1 (0.51) | SERPINE1CNR1CNR2KDM4ETSHR | |
| SCHEMBL1794537 | 0.91 | SERPINE1 (0.59) | SERPINE1CNR1CNR2KDM4EHSD17B10 | |
| SCHEMBL1795693 | 0.91 | SERPINE1 (0.59) | SERPINE1CNR1CNR2KDM4EHSD17B10 | |
| SCHEMBL3872435 | 0.91 | SERPINE1 (0.59) | SERPINE1CNR1CNR2KDM4EHSD17B10 | |
| SCHEMBL1794535 | 0.91 | SERPINE1 (0.59) | SERPINE1CNR1CNR2KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL1800379 | 0.90 | SERPINE1 (0.58) | SERPINE1CNR1CNR2KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL1800136 | 0.90 | SERPINE1 (0.58) | SERPINE1CNR1CNR2KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL1800133 | 0.90 | SERPINE1 (0.58) | SERPINE1CNR1CNR2KDM4EHSD17B10 | |
| SCHEMBL417343 | 0.83 | SERPINE1 (0.60) | SERPINE1CNR1CNR2KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951806-B2 | Plasminogen activator inhibitor-1 inhibitor | RENASCIENCE CO., LTD. (JP) | 2011-05-31 | — | — | US | disclosed |
| US-20090124620-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | RENASCIENCE CO., LTD. (JP) | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124620-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | SERPINE1, SERPINC1, SERPINB1 | SERPINE1 1/4885CNR1 3567/4885CNR2 4684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.