Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14570536 | 0.84 | S1PR4 (0.49) | MEN1KMT2AS1PR4 | |
| SCHEMBL3710075 | 0.83 | PTGDR2 (0.49) | ALDH1A1KDM4EHPGDSMN1; SMN2S1PR4 | |
| SCHEMBL12145951 | 0.82 | S1PR4 (0.44) | ALDH1A1KDM4ENPSR1HPGDMEN1 | |
| SCHEMBL17980858 | 0.82 | ALDH1A1 (0.44) | ALDH1A1KDM4ENPSR1HPGDMEN1 | |
| SCHEMBL5533491 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KDM4ENPSR1HPGDMEN1 | |
| SCHEMBL20116703 | 0.80 | S1PR4 (0.55) | KDM4EHPGDMEN1KMT2AHSD17B10 | |
| SCHEMBL16900169 | 0.77 | ALDH1A1 (0.62) | ALDH1A1KDM4ENPSR1MEN1KMT2A | |
| SCHEMBL13739997 | 0.75 | PTGDR2 (0.60) | ALDH1A1KDM4ENPSR1HPGDMEN1 | |
| SCHEMBL16559854 | 0.75 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL13739761 | 0.74 | PDE10A (0.44) | ALDH1A1KDM4ENPSR1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160221971-A1 | DI-MACROCYCLES | LUMIPHORE, INC. (US) | 2016-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160221971-A1 | DI-MACROCYCLES | DLD, NDC1, MCL1 | ALDH1A1 1827/4885KDM4E 4621/4885NPSR1 1178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.