Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16742593 | 0.83 | KDM4E (0.51) | PTGDR2S1PR4KDM4EPKMHTT | |
| SCHEMBL17972750 | 0.83 | ALDH1A1 (0.47) | S1PR4KDM4EPKMTDP1POLB | |
| SCHEMBL14570557 | 0.83 | S1PR4 (0.56) | PTGDR2S1PR4KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL12145951 | 0.80 | S1PR4 (0.44) | PTGDR2S1PR4KDM4EHTTTDP1 | |
| SCHEMBL16742921 | 0.80 | KDM4E (0.66) | PTGDR2S1PR4KDM4EPKMHTT | |
| SCHEMBL15716449 | 0.80 | PKM (0.47) | PTGDR2KDM4EPKMTDP1POLB | |
| SCHEMBL5532109 | 0.80 | S1PR4 (0.49) | PTGDR2S1PR4KDM4EPKMHTT | |
| SCHEMBL3782032 | 0.80 | PTGDR2 (0.55) | PTGDR2KDM4EPKMTDP1POLB | |
| SCHEMBL3781153 | 0.79 | KDM4E (0.53) | PTGDR2KDM4EPKMHTTTDP1 | |
| SCHEMBL20116703 | 0.77 | S1PR4 (0.55) | S1PR4KDM4ETDP1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396295-A1 | PHENOXY ACETIC ACID DERIVATIVES | Merck Serono S.A. (CH) | 2011-12-21 | — | — | EP | disclosed |
| WO-2010092043-A1 | PHENOXY ACETIC ACID DERIVATIVES | MERCK SERONO S.A. (CH) | 2010-08-19 | — | — | WO | disclosed |