Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | SYK | P43405 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11990357 | 0.99 | SMN1; SMN2 (0.64) | SMN1; SMN2LMNAIDO1SYKL3MBTL1 | |
| SCHEMBL12196470 | 0.91 | SMN1; SMN2 (0.76) | SMN1; SMN2LMNAIDO1SYKL3MBTL1 | |
| SCHEMBL31165330 | 0.91 | SYK (0.58) | SMN1; SMN2LMNAIDO1SYKL3MBTL1 | |
| SCHEMBL15613432 | 0.91 | SYK (0.58) | SMN1; SMN2LMNAIDO1SYKL3MBTL1 | |
| SCHEMBL13531477 | 0.89 | SMN1; SMN2 (0.71) | SMN1; SMN2LMNAIDO1L3MBTL1MAPT | |
| SCHEMBL3830654 | 0.88 | LMNA (0.55) | SMN1; SMN2LMNAIDO1SYKL3MBTL1 | |
| SCHEMBL11990340 | 0.87 | SMN1; SMN2 (0.73) | SMN1; SMN2LMNAIDO1L3MBTL1MAPT | |
| SCHEMBL15516041 | 0.87 | LMNA (0.56) | SMN1; SMN2LMNAIDO1SYKL3MBTL1 | |
| SCHEMBL29248526 | 0.86 | HTT (0.55) | SMN1; SMN2LMNAIDO1SYKL3MBTL1 | |
| SCHEMBL17972739 | 0.85 | LMNA (0.63) | SMN1; SMN2LMNAL3MBTL1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160221971-A1 | DI-MACROCYCLES | LUMIPHORE, INC. (US) | 2016-08-04 | — | — | US | disclosed |
| US-20160221971-A1 | DI-MACROCYCLES | LUMIPHORE, INC. (US) | 2016-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160221971-A1 | DI-MACROCYCLES | DLD, NDC1, MCL1 | SMN1; SMN2 3304/4885LMNA 3243/4885IDO1 1952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.