Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13531477 | 0.94 | SMN1; SMN2 (0.71) | LMNASMN1; SMN2L3MBTL1HTTMAPT | |
| SCHEMBL21338331 | 0.93 | LMNA (0.55) | LMNASMN1; SMN2L3MBTL1HTTMAPT | |
| SCHEMBL11990340 | 0.92 | SMN1; SMN2 (0.73) | LMNASMN1; SMN2L3MBTL1HTTMAPT | |
| SCHEMBL40348 | 0.92 | SMN1; SMN2 (0.63) | LMNASMN1; SMN2L3MBTL1HTTMAPT | |
| SCHEMBL18594580 | 0.87 | SMN1; SMN2 (0.83) | LMNASMN1; SMN2L3MBTL1HTTMAPT | |
| SCHEMBL11990353 | 0.86 | LMNA (0.64) | LMNASMN1; SMN2L3MBTL1HTTMAPT | |
| SCHEMBL17972790 | 0.85 | SMN1; SMN2 (0.63) | LMNASMN1; SMN2L3MBTL1HTTMAPT | |
| SCHEMBL14288938 | 0.85 | LMNA (0.69) | LMNASMN1; SMN2L3MBTL1HTTMAPT | |
| SCHEMBL11990357 | 0.84 | SMN1; SMN2 (0.64) | LMNASMN1; SMN2L3MBTL1HTTMAPT | |
| SCHEMBL8389256 | 0.82 | SMN1; SMN2 (0.74) | LMNASMN1; SMN2L3MBTL1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160221971-A1 | DI-MACROCYCLES | LUMIPHORE, INC. (US) | 2016-08-04 | — | — | US | disclosed |
| US-20160221971-A1 | DI-MACROCYCLES | LUMIPHORE, INC. (US) | 2016-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160221971-A1 | DI-MACROCYCLES | DLD, NDC1, MCL1 | LMNA 3243/4885SMN1; SMN2 3304/4885L3MBTL1 3419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.