SCHEMBL17974009

SCHEMBL17974009

Cc1ccc(S(=O)(=O)NCCc2cccc(Cl)c2)cc1

nearest known ligand 0.69

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.66
MEN1 O00255 2/20 0.66
KMT2A Q03164 2/20 0.66
AKR1C3 P42330 2/20 0.62
TBXA2R P21731 3/20 0.61
CYP19A1 P11511 1/20 0.58
LMNA P02545 1/20 0.56
ADRB2 P07550 1/20 0.55
ADRB1 P08588 1/20 0.55
ADRB3 P13945 1/20 0.55
KDM4E B2RXH2 1/20 0.55
PRMT1 Q99873 1/20 0.53
TAAR1 Q96RJ0 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30822635 1.00 ALDH1A1 (0.66) ALDH1A1MEN1KMT2AAKR1C3TBXA2R
SCHEMBL14751071 0.87 ALDH1A1 (0.71) ALDH1A1MEN1KMT2AAKR1C3CYP19A1
SCHEMBL30822628 0.87 ALDH1A1 (0.71) ALDH1A1MEN1KMT2AAKR1C3CYP19A1
SCHEMBL4617892 0.87 SFRP1 (0.69) ALDH1A1MEN1KMT2AAKR1C3TBXA2R
SCHEMBL5960081 0.86 CYP19A1 (0.80) CYP19A1LMNA
SCHEMBL9131036 0.84 TBXA2R (0.82) ALDH1A1MEN1KMT2AAKR1C3TBXA2R
SCHEMBL2595657 0.83 ALDH1A1 (0.66) ALDH1A1MEN1KMT2AAKR1C3CYP19A1
SCHEMBL28897034 0.82 ALDH1A1 (0.84) ALDH1A1MEN1KMT2ATBXA2RLMNA
SCHEMBL15758883 0.82 L3MBTL1 (0.72) ALDH1A1MEN1KMT2AAKR1C3TBXA2R
SCHEMBL625181 0.82 ALDH1A1 (0.84) ALDH1A1MEN1KMT2APRMT1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924125-A Method for preparing sulfonamide derivative through visible light catalysis without metal participation 苏州大学 2024-04-26 CN disclosed
US-20160222423-A1 ENZYME-CATALYZED ENANTIOSELECTIVE AZIRIDINATION OF OLEFINS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2016-08-04 US disclosed