Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.76 |
| ▸ | MAT2A | P31153 | 3/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL197375 | 0.87 | TSPO (1.00) | TSPOMAT2A | |
| SCHEMBL10042107 | 0.86 | TSPO (0.84) | TSPO | |
| SCHEMBL5745978 | 0.86 | TSPO (0.84) | TSPOMAT2A | |
| SCHEMBL17959426 | 0.85 | TSPO (0.82) | TSPOMAT2A | |
| Hydrochloric Acid SCHEMBL4857420 | 0.85 | TSPO (0.82) | TSPOMAT2A | |
| SCHEMBL4841448 | 0.83 | TSPO (0.78) | TSPOMAT2A | |
| SCHEMBL17959434 | 0.83 | TSPO (0.75) | TSPOMAT2A | |
| SCHEMBL17959432 | 0.83 | TSPO (0.78) | TSPOMAT2A | |
| SCHEMBL17959423 | 0.82 | TSPO (0.83) | TSPOMAT2A | |
| SCHEMBL17974079 | 0.82 | TSPO (0.74) | TSPOMAT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160220704-A1 | PYRIDAZINOINDOLE COMPOUNDS AND METHODS FOR PET IMAGING | VANDERBILT UNIVERSITY | 2016-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160220704-A1 | PYRIDAZINOINDOLE COMPOUNDS AND METHODS FOR PET IMAGING | TSPO, SLC25A17, SLC19A2 | TSPO 1/4885MAT2A 2581/4885MAPK8 3337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.