Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | FOS | P01100 | 1/20 | 0.51 |
| ▸ | JUN | P05412 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17978123 | 0.95 | BCHE (0.59) | BCHEALDH1A1MAOBKMT2AFOS | |
| SCHEMBL28089611 | 0.91 | BCHE (0.66) | BCHEALDH1A1MAOBKMT2AFOS | |
| SCHEMBL2400795 | 0.84 | BCHE (0.68) | BCHEALDH1A1MAOBKMT2AFOS | |
| SCHEMBL2400804 | 0.84 | BCHE (0.68) | BCHEALDH1A1MAOBKMT2AFOS | |
| SCHEMBL11138151 | 0.82 | TTR (0.55) | BCHEP4HB | |
| SCHEMBL28305859 | 0.80 | MAOB (0.47) | BCHEALDH1A1MAOBCYP1A2CYP2D6 | |
| SCHEMBL2400852 | 0.77 | RELA (0.68) | BCHEALDH1A1MAOBKMT2AFOS | |
| SCHEMBL2400847 | 0.77 | RELA (0.68) | BCHEALDH1A1MAOBKMT2AFOS | |
| SCHEMBL3994879 | 0.77 | BCHE (0.62) | BCHEALDH1A1MAOBKMT2AFOS | |
| SCHEMBL2400107 | 0.77 | BCHE (0.62) | BCHEALDH1A1MAOBKMT2AFOS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3256468-A1 | TRICYCLIC COMPOUNDS AND USES THEREOF IN MEDICINE | Sunshine Lake Pharma Co., Ltd. (CN) | 2017-12-20 | — | — | EP | disclosed |
| WO-2016127924-A1 | TRICYCLIC COMPOUNDS AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-08-18 | — | — | WO | disclosed |