Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.66 |
| ▸ | MAOB | P27338 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | FOS | P01100 | 1/20 | 0.55 |
| ▸ | JUN | P05412 | 1/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17978123 | 0.93 | BCHE (0.59) | BCHEMAOBALDH1A1MEN1KMT2A | |
| SCHEMBL17978124 | 0.91 | BCHE (0.58) | BCHEMAOBALDH1A1MEN1KMT2A | |
| SCHEMBL11138151 | 0.82 | TTR (0.55) | BCHE | |
| SCHEMBL10455847 | 0.81 | PLA2G7 (0.53) | BCHEMAOBALDH1A1MEN1KMT2A | |
| SCHEMBL385227 | 0.81 | PLA2G7 (0.53) | BCHEMAOBALDH1A1MEN1KMT2A | |
| SCHEMBL28305859 | 0.80 | MAOB (0.47) | BCHEMAOBALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL21815746 | 0.79 | HSD17B3 (0.53) | MAOBALDH1A1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL21815747 | 0.79 | HSD17B3 (0.53) | MAOBALDH1A1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL8987299 | 0.79 | BCHE (1.00) | BCHEMAOBALDH1A1MEN1KMT2A | |
| SCHEMBL8987297 | 0.79 | BCHE (1.00) | BCHEMAOBALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105218405-B | The synthesis technique of (R, S) 2 [[base of 5 (9 fluorenylmethyloxycarbonyl amino) dibenzo [A, D] cycloheptane 2] oxygen] acetic acid | 上海泰坦科技股份有限公司 | 2017-07-28 | — | — | CN | disclosed |
| CN-104761470-B | The preparation method of (R, S)-2-[[5-(9-fluorenylmethyloxycarbonyl amino) dibenzo [a, d] cycloheptane-2-base] oxygen] acetic acid | 吉尔生化（上海）有限公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-104761470-B | The preparation method of (R, S)-2-[[5-(9-fluorenylmethyloxycarbonyl amino) dibenzo [a, d] cycloheptane-2-base] oxygen] acetic acid | 吉尔生化（上海）有限公司 | 2016-08-24 | — | — | CN | disclosed |