SCHEMBL11138151

SCHEMBL11138151

O=C(O)c1cccc(C=COC(=O)c2ccccc2)c1

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TTR P02766 5/20 0.55
UNG P13051 1/20 0.54
FBP1 P09467 1/20 0.53
P4HB P07237 3/20 0.50
PPARG P37231 1/20 0.47
AKR1C3 P42330 1/20 0.45
KMO O15229 1/20 0.43
PLA2G7 Q13093 1/20 0.42
BCHE P06276 1/20 0.42
SRD5A1 P18405 1/20 0.42
SRD5A2 P31213 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10455847 0.86 PLA2G7 (0.53) PLA2G7BCHE
SCHEMBL385227 0.86 PLA2G7 (0.53) PLA2G7BCHE
SCHEMBL28305859 0.85 MAOB (0.47) TTRUNGPPARGPLA2G7BCHE
SCHEMBL27494117 0.85 KMT2A (0.46) FBP1PLA2G7BCHESRD5A1SRD5A2
SCHEMBL21815747 0.84 HSD17B3 (0.53)
SCHEMBL21815746 0.84 HSD17B3 (0.53)
SCHEMBL3871440 0.83 PLA2G7 (0.49) PLA2G7BCHE
SCHEMBL3871441 0.83 PLA2G7 (0.49) PLA2G7BCHE
SCHEMBL28089611 0.82 BCHE (0.66) BCHE
SCHEMBL17978124 0.82 BCHE (0.58) P4HBBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4376114-A Copolymers of n-vinyl pyrrolidone and a vinylic, allylic or methallylic ester of a cyclic α- or β- carboxylic acid; and cosmetic compositions containing the same SOCIETE ANONYME DITE: L'OREAL (FR) 1983-03-08 US disclosed