Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD10 | O75832 | 1/20 | 0.69 |
| ▸ | CA12 | O43570 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17978568 | 0.97 | PSMD10 (0.65) | PSMD10CA12CA1CA2CA9 | |
| SCHEMBL9382983 | 0.78 | ACHE (0.52) | — | |
| SCHEMBL17978538 | 0.78 | MIF (0.59) | CA12CA1CA2CA9PTGS2 | |
| SCHEMBL17978469 | 0.77 | DDX3X (0.50) | CA12CA1CA2CA9CYP19A1 | |
| SCHEMBL17978492 | 0.76 | PTGS2 (0.51) | CA12CA1CA2CA9CYP19A1 | |
| SCHEMBL17978524 | 0.76 | PTGS2 (0.51) | CA12CA1CA2CA9CYP19A1 | |
| SCHEMBL9325413 | 0.75 | ACHE (0.51) | — | |
| SCHEMBL17978573 | 0.75 | DDX3X (0.55) | CA12CA1CA2CA9CYP19A1 | |
| SCHEMBL17978627 | 0.75 | MIF (0.51) | CA12CA1CA2CA9CYP19A1 | |
| SCHEMBL17978515 | 0.75 | CA12 (0.52) | CA12CA1CA2CA9CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448908-B | Compounds for the treatment of specific leukemias | 拓臻股份有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-115215838-B | Compounds for the treatment of specific leukemias | 拓臻股份有限公司 | 2025-04-04 | — | — | CN | disclosed |
| EP-3256461-B1 | UREA AND SULFONAMIDE DERIVATIVES AS HUMAN HELICASE DDX3 INHIBITORS USEFUL IN THE TREATMENT OF VIRAL DISEASES | AZIENDA OSPEDALIERA UNIV SENESE (IT) | 2023-09-13 | — | — | EP | disclosed |
| EP-3432881-A1 | USE OF DDX3 INHIBITORS AS ANTIPROLIFERATIVE AGENTS | Azienda Ospedaliera Universitaria Senese (IT) | 2019-01-30 | — | — | EP | disclosed |
| EP-3256461-A1 | HUMAN HELICASE DDX3 INHIBITORS AS THERAPEUTIC AGENTS | Azienda Ospedaliera Universitaria Senese (IT) | 2017-12-20 | — | — | EP | disclosed |
| WO-2017162834-A1 | USE OF DDX3 INHIBITORS AS ANTIPROLIFERATIVE AGENTS | AZIENDA OSPEDALIERA UNIVERSITARIA SENESE (IT) | 2017-09-28 | — | — | WO | disclosed |
| WO-2016128541-A1 | HUMAN HELICASE DDX3 INHIBITORS AS THERAPEUTIC AGENTS | AZIENDA OSPEDALIERA UNIVERSITARIA SENESE (IT) | 2016-08-18 | — | — | WO | disclosed |