Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | AOC1 | P19801 | 1/20 | 0.30 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17981868 | 1.00 | LATS1 (0.33) | LATS1SSTR4SLC22A12AOC1AOC3 | |
| SCHEMBL22493240 | 0.79 | LATS1 (0.39) | LATS1SSTR4SLC22A12AOC1AOC3 | |
| SCHEMBL23536732 | 0.74 | P2RX7 (0.35) | — | |
| SCHEMBL22383611 | 0.73 | HTT (0.46) | — | |
| SCHEMBL21503642 | 0.73 | CYP2E1 (0.44) | LATS1SLC22A12AOC1AOC3 | |
| SCHEMBL17981893 | 0.70 | LOXL2 (0.48) | AOC1AOC3 | |
| SCHEMBL19837733 | 0.69 | LATS1 (0.34) | LATS1SLC22A12 | |
| SCHEMBL18019732 | 0.69 | LATS1 (0.34) | LATS1SLC22A12 | |
| SCHEMBL2860576 | 0.69 | DAO (0.41) | — | |
| SCHEMBL19837732 | 0.69 | LATS1 (0.34) | LATS1SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016130396-A1 | MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2016-08-18 | — | — | WO | disclosed |