Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.33 |
| ▸ | AOC1 | P19801 | 2/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | CD38 | P28907 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22493354 | 0.79 | HRH4 (0.37) | LATS1HRH4HRH3AOC1AOC3 | |
| SCHEMBL17981864 | 0.79 | LATS1 (0.33) | LATS1SLC22A12SSTR4AOC1AOC3 | |
| SCHEMBL17981868 | 0.79 | LATS1 (0.33) | LATS1SLC22A12SSTR4AOC1AOC3 | |
| SCHEMBL21503642 | 0.78 | CYP2E1 (0.44) | LATS1SLC22A12AOC1AOC3LIMK1 | |
| SCHEMBL17981893 | 0.75 | LOXL2 (0.48) | AOC1AOC3LOXL2CYP2D6 | |
| SCHEMBL805511 | 0.74 | ALDH1A1 (0.45) | LATS1SLC22A12AOC1AOC3LOXL2 | |
| SCHEMBL28201588 | 0.74 | CACNA1H (0.37) | LATS1SLC22A12SSTR4LOXL2ALDH1A1 | |
| SCHEMBL19997562 | 0.73 | TDP1 (0.44) | — | |
| SCHEMBL17318488 | 0.72 | SCN9A (0.40) | LATS1AOC1AOC3LOXL2ALDH1A1 | |
| SCHEMBL18986509 | 0.71 | LOXL2 (0.57) | AOC1AOC3LOXL2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137506-A1 | COMPOSITIONS AND METHODS FOR IMPROVING NEUROLOGICAL DISEASES AND DISORDERS | CURASEN THERAPEUTICS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| WO-2023225021-A1 | COMPOSITIONS AND METHODS FOR TREATING PATIENTS WITH AMYOTROPHIC LATERAL SCLEROSIS (ALS) | CURASEN THERAPEUTICS, INC. (US) | 2023-11-23 | — | — | WO | disclosed |
| WO-2020198466-A9 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | CURASEN THERAPEUTICS, INC. (US) | 2020-12-30 | — | — | WO | disclosed |
| WO-2020198466-A1 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | CURASEN THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |