SCHEMBL1798304

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1801775	0.92	HPGDS (0.42)	HSD17B10KDM4ELMNAHTTMAPT
	SCHEMBL1798163	0.85	HPGDS (0.53)	HSD17B10KDM4ELMNAHTTMAPT
	SCHEMBL1800509	0.84	CHEK2 (0.47)	KMT2AHPGDS
	SCHEMBL1801232	0.81	HPGDS (0.44)	HSD17B10KDM4ELMNAHTTMAPT
	SCHEMBL1803162	0.79	HPGDS (0.45)	KMT2AHPGDS
	SCHEMBL1797771	0.78	HPGDS (0.65)	MEN1KMT2AHPGDS
	SCHEMBL1800879	0.76	HPGDS (0.55)	HPGDMEN1KMT2AHPGDSRAB9A
	SCHEMBL1800512	0.76	CHEK2 (0.56)	HSD17B10KDM4EHPGDHPGDSRAB9A
	SCHEMBL1799382	0.75	HPGDS (0.52)	HSD17B10KDM4ELMNAHTTMAPT
	SCHEMBL12652593	0.74	CHEK2 (0.40)	HSD17B10KDM4ELMNAMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.