Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15493502 | 0.90 | SMN1; SMN2 (0.37) | SMN1; SMN2NPC1RAB9ATP53HDAC3 | |
| SCHEMBL321300 | 0.87 | SMN1; SMN2 (0.35) | SMN1; SMN2NPC1RAB9ATP53HDAC3 | |
| SCHEMBL15080491 | 0.87 | SMN1; SMN2 (0.35) | SMN1; SMN2NPC1RAB9ATP53HDAC3 | |
| SCHEMBL16491630 | 0.87 | HDAC6 (0.35) | SMN1; SMN2NPC1RAB9ATP53HDAC3 | |
| SCHEMBL3618238 | 0.85 | SMN1; SMN2 (0.37) | SMN1; SMN2NPC1RAB9ATP53HDAC3 | |
| SCHEMBL5150403 | 0.83 | MAPK1 (0.52) | SMN1; SMN2NPC1RAB9ATP53HDAC3 | |
| SCHEMBL14872074 | 0.81 | NAAA (0.52) | SMN1; SMN2NPC1RAB9ATP53HDAC3 | |
| SCHEMBL14868085 | 0.81 | NPC1 (0.45) | SMN1; SMN2NPC1RAB9ATP53HDAC3 | |
| SCHEMBL17928447 | 0.80 | SMN1; SMN2 (0.37) | SMN1; SMN2NPC1RAB9ATP53HDAC3 | |
| SCHEMBL29386113 | 0.80 | MAPT (0.36) | SMN1; SMN2NPC1RAB9ATP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8933218-B2 | Conjugation process for PNAG and a carrier protein | GLAXOSMITHKLINE BIOLOGICALS S.A. (BE) | 2015-01-13 | — | — | US | claimed |
| US-8101423-B2 | Label-free high-throughput optical technique for detecting biomolecular interactions | SRU BIOSYSTEMS, INC. (US) | 2012-01-24 | — | — | US | claimed |
| US-20090148955-A1 | Label-Free High-Throughput Optical Technique for Detecting Biomolecular Interactions | SRU BIOSYSTEMS, INC. | 2009-06-11 | — | — | US | claimed |
| JP-4202140-B2 | — | — | 2008-12-24 | — | — | JP | claimed |
| US-7435385-B2 | Label-free high-throughput optical technique for detecting biomolecular interactions | SRU BIOSYSTEMS, INC. (US) | 2008-10-14 | — | — | US | claimed |
| EP-1892518-A2 | A label-free high throughput optical technique for detecting bio-molecular interactions | SRU Biosystems, Inc. (US) | 2008-02-27 | — | — | EP | claimed |
| EP-1468290-A4 | A GUIDED MODE RESONANT FILTER BIOSENSOR USING A LINEAR GRATING SURFACE STRUCTURE | SRU BIOSYSTEMS INC (US) | 2006-09-27 | — | — | EP | claimed |
| EP-1468290-A2 | A GUIDED MODE RESONANT FILTER BIOSENSOR USING A LINEAR GRATING SURFACE STRUCTURE | Sru Biosystems, LLC (US) | 2004-10-20 | — | — | EP | claimed |
| JP-2004529324-A | — | — | 2004-09-24 | — | — | JP | claimed |
| US-20040151626-A1 | Label-free high-throughput optical technique for detecting biomolecular interactions | X-BODY, INC. | 2004-08-05 | — | — | US | claimed |
| EP-1337847-A1 | A LABEL-FREE HIGH-THROUGHPUT OPTICAL TECHNIQUE FOR DETECTING BIOMOLECULAR INTERACTIONS | Sru Biosystems, LLC (US) | 2003-08-27 | — | — | EP | claimed |
| WO-2003064995-A2 | A GUIDED MODE RESONANT FILTER BIOSENSOR USING A LINEAR GRATING SURFACE STRUCTURE | SRU BIOSYSTEMS, LLC (US) | 2003-08-07 | — | — | WO | claimed |
| US-20030027328-A1 | Guided mode resonant filter biosensor using a linear grating surface structure | SRU BIOSYSTEMS, LLC | 2003-02-06 | — | — | US | claimed |
| US-20020127565-A1 | Biosensor for use in detecting and monitoring biopolymer activity in sample | SRU BIOSYSTEMS, LLC | 2002-09-12 | — | — | US | claimed |
| WO-2002061429-A2 | A LABEL-FREE HIGH-THROUGHPUT OPTICAL TECHNIQUE FOR DETECTING BIOMOLECULAR INTERACTIONS | SRU BIOSYSTEMS, LLC (US) | 2002-08-08 | — | — | WO | claimed |
| US-8580578-B2 | Optical detection of label-free biomolecular interactions using microreplicated plastic | X-BODY, INC. (US) | 2013-11-12 | — | — | US | disclosed |
| US-20120101230-A1 | HIGH-DENSITY POLYMER SURFACE COATING TO IMMOBILIZE CHEMICAL OR BIOLOGICAL MOLECULES | X-BODY, INC. | 2012-04-26 | — | — | US | disclosed |
| US-20020127565-A1 | Biosensor for use in detecting and monitoring biopolymer activity in sample | SRU BIOSYSTEMS, LLC | 2002-09-12 | — | — | US | disclosed |
| WO-2002061429-A2 | A LABEL-FREE HIGH-THROUGHPUT OPTICAL TECHNIQUE FOR DETECTING BIOMOLECULAR INTERACTIONS | SRU BIOSYSTEMS, LLC (US) | 2002-08-08 | — | — | WO | disclosed |
| WO-2002059602-A2 | A LABEL-FREE HIGH-THROUGHPUT OPTICAL TECHNIQUE FOR DETECTING BIOMOLECULAR INTERACTIONS | SRU BIOSYSTEMS, LLC (US) | 2002-08-01 | — | — | WO | disclosed |