Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PTAFR | P25105 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15493502 | 0.91 | SMN1; SMN2 (0.37) | SMN1; SMN2NPC1RAB9ATP53HDAC3 | |
| SCHEMBL321300 | 0.89 | SMN1; SMN2 (0.35) | SMN1; SMN2NPC1RAB9ATP53HDAC3 | |
| SCHEMBL16491630 | 0.88 | HDAC6 (0.35) | SMN1; SMN2NPC1RAB9ATP53HDAC3 | |
| SCHEMBL179849 | 0.87 | SMN1; SMN2 (0.40) | SMN1; SMN2NPC1RAB9ATP53HDAC3 | |
| SCHEMBL900949 | 0.81 | SMN1; SMN2 (0.36) | SMN1; SMN2NPC1RAB9ATP53HDAC3 | |
| SCHEMBL14883315 | 0.81 | HPGD (0.37) | SMN1; SMN2HDAC3HDAC6ALDH1A1HDAC1 | |
| SCHEMBL15489464 | 0.80 | NPC1 (0.36) | SMN1; SMN2NPC1RAB9ATP53NFKB1 | |
| SCHEMBL17928447 | 0.78 | SMN1; SMN2 (0.37) | SMN1; SMN2NPC1RAB9ATP53HDAC3 | |
| SCHEMBL5150403 | 0.78 | MAPK1 (0.52) | SMN1; SMN2NPC1RAB9ATP53HDAC3 | |
| SCHEMBL30031578 | 0.77 | ALDH1A1 (0.33) | SMN1; SMN2HDAC3HDAC6KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11701433-B2 | Complexes for delivery of antigenic peptides | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2023-07-18 | — | — | US | disclosed |
| US-20180221500-A1 | Environmentally Sensitive Compositions and Methods of Use Thereof | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES | 2018-08-09 | — | — | US | disclosed |
| US-9814781-B2 | Environmentally sensitive compositions and methods of use thereof | RHODE ISLAND COUNCIL ON POSTSECONDARY EDUCATION (STATUTORY SUCCESSOR TO RHODE ISLAND BOARD OF GOVERNORS FOR HIGHER EDUCATION) (US) | 2017-11-14 | — | — | US | disclosed |
| US-20160256560-A1 | Environmentally Sensitive Compositions | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES | 2016-09-08 | — | — | US | disclosed |
| US-9289508-B2 | Environmentally sensitive compositions and methods of use in the treatment and diagnosis of tumors | UNIVERSITY OF RHODE ISLAND (US) | 2016-03-22 | — | — | US | disclosed |
| US-20150051153-A1 | Environmentally Sensitive Compositions | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES | 2015-02-19 | — | — | US | disclosed |
| US-8475765-B2 | Hydroxyalkyl starch derivatives | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2013-07-02 | — | — | US | disclosed |
| US-20110054152-A1 | Hydroxyalkyl Starch Derivatives | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11701433-B2 | Complexes for delivery of antigenic peptides | IFNG, ALB, IFNAR1 | SMN1; SMN2 1621/4885NPC1 2759/4885RAB9A 1348/4885 |
| US-20110054152-A1 | Hydroxyalkyl Starch Derivatives | GRHPR, DCXR, HRH2 | SMN1; SMN2 4388/4885NPC1 2773/4885RAB9A 2792/4885 |
| US-20150051153-A1 | Environmentally Sensitive Compositions | PHLPP1, PHLPP2, FABP2 | SMN1; SMN2 3719/4885NPC1 2275/4885RAB9A 1144/4885 |
| US-20180221500-A1 | Environmentally Sensitive Compositions and Methods of Use Thereof | PHLPP1, PHLPP2, FABP2 | SMN1; SMN2 3759/4885NPC1 2211/4885RAB9A 1614/4885 |
| US-20160256560-A1 | Environmentally Sensitive Compositions | PHLPP1, PHLPP2, FABP2 | SMN1; SMN2 3719/4885NPC1 2275/4885RAB9A 1144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.