Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PTAFR | P25105 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179849 | 0.85 | SMN1; SMN2 (0.40) | SMN1; SMN2RAB9ANPC1TP53NFKB1 | |
| SCHEMBL16279731 | 0.84 | RAB9A (0.38) | SMN1; SMN2RAB9ANPC1TP53PTAFR | |
| SCHEMBL15994284 | 0.80 | HPGD (0.38) | LMNAALDH1A1 | |
| SCHEMBL14868085 | 0.79 | NPC1 (0.45) | SMN1; SMN2RAB9ANPC1TP53NFKB1 | |
| SCHEMBL18726765 | 0.78 | HDAC1 (0.40) | LMNAALDH1A1HDAC6 | |
| SCHEMBL1389471 | 0.78 | LMNA (0.34) | SMN1; SMN2RAB9ANPC1KMT2ALMNA | |
| SCHEMBL29386113 | 0.77 | MAPT (0.36) | SMN1; SMN2RAB9ANPC1TP53KMT2A | |
| SCHEMBL42875 | 0.77 | MAPT (0.36) | SMN1; SMN2RAB9ANPC1TP53KMT2A | |
| SCHEMBL321300 | 0.77 | SMN1; SMN2 (0.35) | SMN1; SMN2RAB9ANPC1TP53PTAFR | |
| SCHEMBL14872074 | 0.76 | NAAA (0.52) | SMN1; SMN2RAB9ANPC1TP53NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160074042-A1 | NEURAL IMPLANT | MEDIZINISCHE HOCHSCHULE HANNOVER (DE) | 2016-03-17 | — | — | US | disclosed |
| US-8696762-B2 | Implant of cross-linked spider silk threads | MEDIZINISCHE HOCHSCHULE HANNOVER (DE) | 2014-04-15 | — | — | US | disclosed |
| US-20130190786-A1 | NEURAL IMPLANT | MEDIZINISCHE HOCHSCHULE HANNOVER (DE) | 2013-07-25 | — | — | US | disclosed |
| EP-2097117-B1 | IMPLANT OF CROSS-LINKED SPIDER SILK THREADS | HANNOVER MED HOCHSCHULE (DE) | 2013-05-22 | — | — | EP | disclosed |
| US-20100228359-A1 | IMPLANT OF CROSS-LINKED SPIDER SILK THREADS | MEDIZINISCHE HOCHSCHULE HANNOVER (DE) | 2010-09-09 | — | — | US | disclosed |
| EP-2097117-A1 | IMPLANT OF CROSS-LINKED SPIDER SILK THREADS | Medizinische Hochschule Hannover (DE) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008071226-A1 | IMPLANT OF CROSS-LINKED SPIDER SILK THREADS | MEDIZINISCHE HOCHSCHULE HANNOVER (DE) | 2008-06-19 | — | — | WO | disclosed |