Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | XIAP | P98170 | 1/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | CPA3 | P15088 | 3/20 | 0.42 |
| ▸ | CPA1 | P15085 | 2/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | CPB1 | P15086 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.42 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1798536 | 1.00 | SLC1A3 (0.49) | SLC1A3SLC1A2SLC1A1ALPIPKM | |
| SCHEMBL6552292 | 0.85 | GRIK1 (0.44) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7335142 | 0.85 | ALPI (0.50) | SLC1A3SLC1A2SLC1A1ALPIPKM | |
| SCHEMBL7335152 | 0.85 | ALPI (0.50) | SLC1A3SLC1A2SLC1A1ALPIPKM | |
| SCHEMBL2927474 | 0.83 | SLC1A3 (0.45) | SLC1A3SLC1A2SLC1A1ALPIPKM | |
| SCHEMBL2927472 | 0.83 | SLC1A3 (0.45) | SLC1A3SLC1A2SLC1A1ALPIPKM | |
| SCHEMBL1764172 | 0.82 | ALPI (0.47) | SLC1A3SLC1A2SLC1A1ALPIPKM | |
| SCHEMBL434524 | 0.79 | ALPI (0.55) | SLC1A3SLC1A2SLC1A1ALPIPKM | |
| SCHEMBL434525 | 0.79 | ALPI (0.55) | SLC1A3SLC1A2SLC1A1ALPIPKM | |
| SCHEMBL2466759 | 0.78 | CYP1A2 (0.57) | SLC1A3SLC1A2SLC1A1ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951943-B2 | Method for preparing and purifying 3-hydroxyamidinophenylalanine compounds | WILEX AG (DE) | 2011-05-31 | — | — | US | claimed |
| EP-1799665-B1 | METHOD FOR CLEANING 3-HYDROXYAMIDINOPHENYLALANINE DERIVATIVES BY THE PRECIPITATION AND RECRYSTALLISATION OF A SALT AND AN AROMATIC SULPHONIC ACID | WILEX AG (DE) | 2009-08-19 | — | — | EP | claimed |
| US-20090099360-A9 | Method for Cleaning 3-Hydroxyamidinophenylalanine Derivatives by the Precepitation and Recrystallization of Salt and an Aromatic Sulfonic Acid | WILEX AG (DE) | 2009-04-16 | — | — | US | claimed |
| US-20080039626-A1 | Method for Cleaning 3-Hydroxyamidinophenylalanine Derivatives by the Precepitation and Recrystallization of Salt and an Aromatic Sulfonic Acid | WILEX AG (DE) | 2008-02-14 | — | — | US | claimed |
| CN-114105910-A | Hydroxyamidinophenylalanine derivative, pharmaceutical composition and application | 北京悦康科创医药科技股份有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-114105910-A | Hydroxyamidinophenylalanine derivative, pharmaceutical composition and application | 北京悦康科创医药科技股份有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-114105910-A | Hydroxyamidinophenylalanine derivative, pharmaceutical composition and application | 北京悦康科创医药科技股份有限公司 | 2022-03-01 | — | — | CN | disclosed |
| US-9089532-B2 | Stable dosage form of phenylalanine derivatives | WILEX AG (DE) | 2015-07-28 | — | — | US | disclosed |
| US-7951943-B2 | Method for preparing and purifying 3-hydroxyamidinophenylalanine compounds | WILEX AG (DE) | 2011-05-31 | — | — | US | disclosed |
| US-20090099360-A9 | Method for Cleaning 3-Hydroxyamidinophenylalanine Derivatives by the Precepitation and Recrystallization of Salt and an Aromatic Sulfonic Acid | WILEX AG (DE) | 2009-04-16 | — | — | US | disclosed |
| US-20080039626-A1 | Method for Cleaning 3-Hydroxyamidinophenylalanine Derivatives by the Precepitation and Recrystallization of Salt and an Aromatic Sulfonic Acid | WILEX AG (DE) | 2008-02-14 | — | — | US | disclosed |
| US-20070244127-A1 | Stable Dosage Form of Phenylalanine Derivatives | WILEX AG (DE) | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244127-A1 | Stable Dosage Form of Phenylalanine Derivatives | FAP, PAH, PEPD | SLC1A3 785/4885SLC1A2 970/4885SLC1A1 910/4885 |
| US-20090099360-A9 | Method for Cleaning 3-Hydroxyamidinophenylalanine Derivatives by the Precepitation and Recrystallization of Salt and an Aromatic Sulfonic Acid | PEPD, PAH, PRSS3 | SLC1A3 1237/4885SLC1A2 1733/4885SLC1A1 1357/4885 |
| US-20080039626-A1 | Method for Cleaning 3-Hydroxyamidinophenylalanine Derivatives by the Precepitation and Recrystallization of Salt and an Aromatic Sulfonic Acid | PEPD, PAH, PRSS3 | SLC1A3 1237/4885SLC1A2 1733/4885SLC1A1 1357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.