Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.42 |
| ▸ | ANPEP | P15144 | 3/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | LAP3 | P28838 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1798536 | 0.85 | SLC1A3 (0.49) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1798535 | 0.85 | SLC1A3 (0.49) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10482476 | 0.77 | AOC3 (0.47) | GRIK1ERAP1ANPEPERAP2CNR2 | |
| SCHEMBL23064152 | 0.76 | TSHR (0.49) | GRIK1CNR2TSHRALOX5 | |
| SCHEMBL3663595 | 0.76 | PPARG (0.46) | GRIK1ERAP1ANPEPERAP2CNR2 | |
| SCHEMBL23064151 | 0.76 | TSHR (0.49) | GRIK1CNR2TSHRALOX5 | |
| SCHEMBL4925880 | 0.74 | ALOX5 (0.51) | GRIK1ALOX5 | |
| SCHEMBL7335142 | 0.73 | ALPI (0.50) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7335152 | 0.73 | ALPI (0.50) | SLC1A3SLC1A2SLC1A1 | |
| Hydrochloric Acid SCHEMBL8190926 | 0.72 | ALDH1A1 (0.47) | GRIK1ERAP1ANPEPERAP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1483285-A1 | INHIBITORS OF THE BLOOD-CLOTTING FACTOR Xa, PRODUCTION THEREOF AND USE OF THE SAME | Curacyte AG (DE) | 2004-12-08 | — | — | EP | claimed |
| WO-2003076457-A1 | INHIBITORS OF THE BLOOD-CLOTTING FACTOR Xa, PRODUCTION THEREOF AND USE OF THE SAME | CURACYTE AG (DE) | 2003-09-18 | — | — | WO | claimed |