Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844036 | 0.91 | POLB (0.43) | POLBMEN1KMT2ALRRK2SCN10A | |
| SCHEMBL17844159 | 0.90 | POLB (0.42) | POLBMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL17986795 | 0.85 | POLB (0.47) | POLBMEN1KMT2ASCN10ASMN1; SMN2 | |
| SCHEMBL29360277 | 0.83 | POLB (0.48) | POLBMEN1KMT2ALRRK2ALDH1A1 | |
| SCHEMBL14684583 | 0.83 | POLB (0.48) | POLBMEN1KMT2ALRRK2ALDH1A1 | |
| SCHEMBL15947511 | 0.83 | POLB (0.47) | POLBMEN1KMT2ALRRK2L3MBTL1 | |
| SCHEMBL29904936 | 0.82 | POLB (0.39) | POLBLRRK2ALDH1A1 | |
| SCHEMBL17844096 | 0.82 | POLB (0.39) | POLBLRRK2ALDH1A1 | |
| SCHEMBL17329176 | 0.81 | POLB (0.46) | POLBMEN1KMT2ALRRK2L3MBTL1 | |
| SCHEMBL18401201 | 0.81 | POLB (0.45) | POLBMEN1KMT2ALRRK2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10266552-B2 | Condensed heterocyclic compound having cycloalkylpyridyl group or salt thereof, agricultural and horticultural insecticide comprising the compound, and method for using the insecticide | NIHON NOHYAKU CO., LTD. (JP) | 2019-04-23 | — | — | US | disclosed |
| WO-2016121997-A1 | FUSED HETEROCYCLIC COMPOUND HAVING CYCLOALKYLPYRIDYL GROUP OR SALT THEREOF, AND AGRICULTURAL OR HORTICULTURAL INSECTICIDE CONTAINING SAID COMPOUND AND USE METHOD THEREFOR | 日本農薬株式会社 | 2016-08-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10266552-B2 | Condensed heterocyclic compound having cycloalkylpyridyl group or salt thereof, agricultural and horticultural insecticide comprising the compound, and method for using the insecticide | DDT, HCN3, HCN1 | POLB 3724/4885MEN1 748/4885KMT2A 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.