Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29904936 | 1.00 | POLB (0.39) | POLBTRPM8DDR1TNFALDH1A1 | |
| SCHEMBL17858042 | 0.97 | POLB (0.38) | POLBTRPM8DDR1TNFALDH1A1 | |
| SCHEMBL17609373 | 0.96 | POLB (0.37) | POLBTRPM8DDR1TNFALDH1A1 | |
| SCHEMBL17609372 | 0.93 | POLB (0.36) | POLBTRPM8DDR1TNFALDH1A1 | |
| SCHEMBL24696189 | 0.91 | POLB (0.38) | POLBTRPM8TNF | |
| SCHEMBL30122145 | 0.91 | POLB (0.38) | POLBTRPM8TNF | |
| SCHEMBL30401655 | 0.91 | POLB (0.38) | POLBTRPM8TNF | |
| SCHEMBL21586201 | 0.91 | POLB (0.38) | POLBTRPM8TNF | |
| SCHEMBL29748523 | 0.87 | — | — | |
| SCHEMBL17844106 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317119-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-10-14 | — | — | US | disclosed |
| US-20210317119-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-10-14 | — | — | US | disclosed |
| US-11072608-B2 | Pesticidally active heterocyclic derivatives with sulphur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2021-07-27 | — | — | US | disclosed |
| US-11072608-B2 | Pesticidally active heterocyclic derivatives with sulphur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2021-07-27 | — | — | US | disclosed |
| CN-107207460-B | Fused heterocyclic compound having cycloalkylpyridyl group or salt thereof, agricultural and horticultural insecticide containing the same, and method for using the same | 日本农药株式会社 | 2020-09-15 | — | — | CN | disclosed |
| EP-3233851-B1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-27 | — | — | EP | disclosed |
| EP-3233851-B1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-27 | — | — | EP | disclosed |
| EP-3252046-B1 | FUSED HETEROCYCLIC COMPOUND HAVING CYCLOALKYLPYRIDYL GROUP OR SALT THEREOF, AND AGRICULTURAL OR HORTICULTURAL INSECTICIDE CONTAINING SAID COMPOUND AND USE METHOD THEREFOR | NIHON NOHYAKU CO LTD (JP) | 2020-04-01 | — | — | EP | disclosed |
| US-20190308971-A1 | PESTICIDALLY ACTIVE HETROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-10-10 | — | — | US | disclosed |
| US-20190308971-A1 | PESTICIDALLY ACTIVE HETROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-10-10 | — | — | US | disclosed |
| US-10266552-B2 | Condensed heterocyclic compound having cycloalkylpyridyl group or salt thereof, agricultural and horticultural insecticide comprising the compound, and method for using the insecticide | NIHON NOHYAKU CO., LTD. (JP) | 2019-04-23 | — | — | US | disclosed |
| US-20180002347-A1 | CONDENSED HETEROCYCLIC COMPOUND HAVING CYCLOALKYLPYRIDYL GROUP OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE INSECTICIDE | NIHON NOHYAKU CO., LTD. (JP) | 2018-01-04 | — | — | US | disclosed |
| EP-3252046-A1 | FUSED HETEROCYCLIC COMPOUND HAVING CYCLOALKYLPYRIDYL GROUP OR SALT THEREOF, AND AGRICULTURAL OR HORTICULTURAL INSECTICIDE CONTAINING SAID COMPOUND AND USE METHOD THEREFOR | Nihon Nohyaku Co., Ltd. (JP) | 2017-12-06 | — | — | EP | disclosed |
| US-20170342065-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-11-30 | — | — | US | disclosed |
| US-20170342065-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-11-30 | — | — | US | disclosed |
| US-20170342065-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-11-30 | — | — | US | disclosed |
| EP-3233851-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | Syngenta Participations AG (CH) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016121997-A1 | FUSED HETEROCYCLIC COMPOUND HAVING CYCLOALKYLPYRIDYL GROUP OR SALT THEREOF, AND AGRICULTURAL OR HORTICULTURAL INSECTICIDE CONTAINING SAID COMPOUND AND USE METHOD THEREFOR | 日本農薬株式会社 | 2016-08-04 | — | — | WO | disclosed |
| WO-2016096584-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-23 | — | — | WO | disclosed |
| WO-2016096584-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11072608-B2 | Pesticidally active heterocyclic derivatives with sulphur containing substituents | DDT, ACHE, GSTM1 | POLB 4235/4885TRPM8 870/4885DDR1 4364/4885 |
| US-20210317119-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | DDT, ACHE, GSTM1 | POLB 4395/4885TRPM8 665/4885DDR1 4471/4885 |
| US-20170342065-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | DDT, ACHE, GSTM1 | POLB 4325/4885TRPM8 703/4885DDR1 4555/4885 |
| US-20180002347-A1 | CONDENSED HETEROCYCLIC COMPOUND HAVING CYCLOALKYLPYRIDYL GROUP OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE INSECTICIDE | DDT, HCN3, HCN1 | POLB 3724/4885TRPM8 885/4885DDR1 3696/4885 |
| US-20190308971-A1 | PESTICIDALLY ACTIVE HETROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | DDT, GSTO1, GSTM1 | POLB 4410/4885TRPM8 671/4885DDR1 4274/4885 |
| US-10266552-B2 | Condensed heterocyclic compound having cycloalkylpyridyl group or salt thereof, agricultural and horticultural insecticide comprising the compound, and method for using the insecticide | DDT, HCN3, HCN1 | POLB 3724/4885TRPM8 885/4885DDR1 3696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.