Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15398683 | 0.85 | NPC1 (0.39) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL17988719 | 0.84 | MAPT (0.45) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL17988681 | 0.81 | SLC22A6 (0.44) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL14699614 | 0.77 | MAPT (0.50) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL17988686 | 0.77 | MAPT (0.50) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL17988664 | 0.76 | CISD1 (0.43) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL15398853 | 0.75 | LMNA (0.34) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL12817727 | 0.75 | MAPT (0.55) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL14699619 | 0.75 | MAPT (0.55) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL17991980 | 0.75 | MAPT (0.48) | MAPTNPC1RAB9AKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9409859-B2 | Substituted diphenyl derivatives | CREATIVE THERAPEUTICS GMBH (DE) | 2016-08-09 | — | — | US | disclosed |
| US-9409859-B2 | Substituted diphenyl derivatives | CREATIVE THERAPEUTICS GMBH (DE) | 2016-08-09 | — | — | US | disclosed |