SCHEMBL17988686

SCHEMBL17988686

CN(C)N=Nc1ccc(C(=O)c2ccc(OS(=O)(=O)O)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.50
▸ RAB9A P51151 3/20 0.50
▸ NPC1 O15118 3/20 0.50
▸ ALDH1A1 P00352 3/20 0.46
▸ LMNA P02545 1/20 0.45
▸ STS P08842 7/20 0.45
▸ KDM4E B2RXH2 2/20 0.37
▸ CYP1A2 P05177 1/20 0.36
▸ MAPK1 P28482 1/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ POLB P06746 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14699614 1.00 MAPT (0.50) MAPTRAB9ANPC1ALDH1A1LMNA
SCHEMBL26771623 0.89 MAPT (0.50) MAPTRAB9ANPC1ALDH1A1LMNA
SCHEMBL15398648 0.87 STS (0.64) MAPTRAB9ANPC1ALDH1A1LMNA
SCHEMBL17991992 0.87 LMNA (0.49) MAPTRAB9ANPC1ALDH1A1LMNA
SCHEMBL17991980 0.85 MAPT (0.48) MAPTRAB9ANPC1ALDH1A1LMNA
SCHEMBL17992003 0.84 MAPT (0.44) MAPTRAB9ANPC1ALDH1A1LMNA
SCHEMBL17992004 0.84 LMNA (0.54) MAPTRAB9ANPC1ALDH1A1LMNA
SCHEMBL17991985 0.83 LMNA (0.45) MAPTRAB9ANPC1ALDH1A1LMNA
SCHEMBL17991993 0.83 LMNA (0.45) MAPTRAB9ANPC1ALDH1A1LMNA
SCHEMBL17991987 0.83 MAPT (0.43) MAPTRAB9ANPC1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230355644-A1 ACTIVE INGREDIENTS AND DRUGS FOR THE THERAPY OF VIRAL DISEASES, ESPECIALLY CORONA INFECTIONS, ESPECIALLY COVID-19 CREATIVE THERAPEUTICS GMBH (DE) 2023-11-09 — — US disclosed
US-9409859-B2 Substituted diphenyl derivatives CREATIVE THERAPEUTICS GMBH (DE) 2016-08-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230355644-A1 ACTIVE INGREDIENTS AND DRUGS FOR THE THERAPY OF VIRAL DISEASES, ESPECIALLY CORONA INFECTIONS, ESPECIALLY COVID-19 ACE, ACE2, SARS1 MAPT 847/4885RAB9A 2059/4885NPC1 298/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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