Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | STAT1 | P42224 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | STS | P08842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15399109 | 0.88 | ALDH1A1 (0.48) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL17992003 | 0.86 | MAPT (0.44) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL17988686 | 0.85 | MAPT (0.50) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL14699614 | 0.85 | MAPT (0.50) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL17988720 | 0.82 | BRD4 (0.33) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL17988681 | 0.77 | SLC22A6 (0.44) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL17992004 | 0.76 | LMNA (0.54) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL17991992 | 0.76 | LMNA (0.49) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL17988719 | 0.75 | MAPT (0.45) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL26771623 | 0.75 | MAPT (0.50) | MAPTNPC1RAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9409859-B2 | Substituted diphenyl derivatives | CREATIVE THERAPEUTICS GMBH (DE) | 2016-08-09 | — | — | US | disclosed |