Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.34 |
| ▸ | FEN1 | P39748 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17987933 | 0.84 | CYP3A4 (0.46) | COMTGAATDP1KDM4EMAPT | |
| SCHEMBL17992229 | 0.83 | COMT (0.40) | COMTGAATDP1KDM4EMAPT | |
| SCHEMBL19676465 | 0.83 | COMT (0.40) | COMTGAATDP1KDM4EMAPT | |
| SCHEMBL17992223 | 0.83 | COMT (0.40) | COMTGAATDP1KDM4EMAPT | |
| SCHEMBL19404373 | 0.83 | COMT (0.47) | COMTGAATDP1KDM4EMAPT | |
| SCHEMBL20710642 | 0.82 | P4HTM (0.49) | COMTMAPTSMN1; SMN2TRPV1 | |
| SCHEMBL19676473 | 0.82 | COMT (0.40) | COMTGAATDP1KDM4EMAPT | |
| SCHEMBL20965434 | 0.81 | CYP2A6 (0.43) | COMTALOX5APFEN1 | |
| SCHEMBL19767067 | 0.81 | CYP2D6 (0.40) | COMTTDP1MAPTALDH1A1LMNA | |
| SCHEMBL20710640 | 0.81 | COMT (0.39) | COMTGAATDP1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3252042-B1 | BIPYRIDINE COMPOUND AND USE OF SAME FOR NOXIOUS ARTHROPOD CONTROL | SUMITOMO CHEMICAL CO (JP) | 2020-03-18 | — | — | EP | disclosed |
| US-10173997-B2 | Bipyridine compound and use of same for noxious arthropod control | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2019-01-08 | — | — | US | disclosed |
| US-10172356-B2 | Bipyridine compound and use of same for noxious arthropod control | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2019-01-08 | — | — | US | disclosed |
| US-20180009778-A1 | BIPYRIDINE COMPOUND AND USE OF SAME FOR NOXIOUS ARTHROPOD CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-01-11 | — | — | US | disclosed |
| EP-3252042-A1 | BIPYRIDINE COMPOUND AND USE OF SAME FOR NOXIOUS ARTHROPOD CONTROL | Sumitomo Chemical Company, Limited (JP) | 2017-12-06 | — | — | EP | disclosed |
| WO-2017073733-A1 | PEST CONTROL COMPOSITION AND USE THEREOF | 住友化学株式会社 | 2017-05-04 | — | — | WO | disclosed |
| WO-2016121969-A1 | BIPYRIDINE COMPOUND AND USE OF SAME FOR NOXIOUS ARTHROPOD CONTROL | 住友化学株式会社 | 2016-08-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10172356-B2 | Bipyridine compound and use of same for noxious arthropod control | HSPA5, BBOX1, ACHE | COMT 2347/4885GAA 3559/4885TDP1 3702/4885 |
| US-20180009778-A1 | BIPYRIDINE COMPOUND AND USE OF SAME FOR NOXIOUS ARTHROPOD CONTROL | BBOX1, ACHE, MORF4L1 | COMT 1430/4885GAA 3998/4885TDP1 4008/4885 |
| US-10173997-B2 | Bipyridine compound and use of same for noxious arthropod control | BBOX1, ACHE, MORF4L1 | COMT 1430/4885GAA 3998/4885TDP1 4008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.