Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19486165 | 0.91 | L3MBTL1 (0.41) | L3MBTL1POLBHPGDALDH1A1MAPT | |
| SCHEMBL12801036 | 0.91 | KDM4E (0.47) | L3MBTL1POLBHPGDALDH1A1MAPT | |
| SCHEMBL15631628 | 0.91 | LCK (0.43) | L3MBTL1POLBHPGDALDH1A1MAPT | |
| SCHEMBL25877487 | 0.91 | KDM4E (0.42) | L3MBTL1ALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL18083415 | 0.90 | KDM4E (0.43) | L3MBTL1POLBHPGDALDH1A1MAPT | |
| SCHEMBL16920086 | 0.89 | KDM4E (0.45) | L3MBTL1POLBHPGDALDH1A1MAPT | |
| SCHEMBL17032362 | 0.89 | GPR3 (0.40) | L3MBTL1POLBHPGDALDH1A1MAPT | |
| SCHEMBL21346769 | 0.89 | KDM4E (0.40) | L3MBTL1POLBHPGDALDH1A1MAPT | |
| SCHEMBL12801035 | 0.89 | KDM4E (0.42) | L3MBTL1POLBHPGDALDH1A1MAPT | |
| SCHEMBL17850696 | 0.88 | KMT2A (0.34) | L3MBTL1POLBHPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3054498-B1 | BISIMIDAZODIAZOCINES | IDEMITSU KOSAN CO (JP) | 2017-09-20 | — | — | EP | disclosed |
| WO-2016125110-A1 | BISIMIDAZOLODIAZOCINES | IDEMITSU KOSAN CO., LTD. (JP) | 2016-08-11 | — | — | WO | disclosed |
| EP-3054498-A1 | Bisimidazodiazocines | Idemitsu Kosan Co., Ltd. (JP) | 2016-08-10 | — | — | EP | disclosed |