SCHEMBL17993428

SCHEMBL17993428

Cc1ccccc1-c1nc(-c2ccccc2)nc(-c2ccccc2)n1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.61
CYP1A2 P05177 6/20 0.54
TSHR P16473 4/20 0.54
CYP2C19 P33261 4/20 0.54
CLK4 Q9HAZ1 4/20 0.54
CYP2D6 P10635 3/20 0.54
MAPK1 P28482 2/20 0.54
DPP4 P27487 1/20 0.53
CYP3A4 P08684 4/20 0.50
ALOX15 P16050 3/20 0.50
HSD17B10 Q99714 3/20 0.50
ADORA3 P0DMS8 2/20 0.50
ADORA2A P29274 2/20 0.50
ADORA2B P29275 2/20 0.50
ADORA1 P30542 2/20 0.50
USP2 O75604 1/20 0.50
NPC1 O15118 4/20 0.48
SMN1; SMN2 Q16637 4/20 0.48
RAB9A P51151 3/20 0.48
ALDH1A1 P00352 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18732399 0.96 L3MBTL1 (0.57) L3MBTL1CYP1A2TSHRCYP2C19CLK4
SCHEMBL26195602 0.94 L3MBTL1 (0.73) L3MBTL1CYP1A2TSHRCYP2C19CLK4
SCHEMBL21742574 0.92 L3MBTL1 (0.57) L3MBTL1CYP1A2TSHRCYP2C19CLK4
SCHEMBL10046782 0.91 L3MBTL1 (0.52) L3MBTL1CYP1A2TSHRCYP2C19CLK4
SCHEMBL19762128 0.91 L3MBTL1 (0.52) L3MBTL1CYP1A2TSHRCYP2C19CLK4
SCHEMBL19762150 0.91 L3MBTL1 (0.52) L3MBTL1CYP1A2TSHRCYP2C19CLK4
SCHEMBL19762190 0.91 L3MBTL1 (0.52) L3MBTL1CYP1A2TSHRCYP2C19CLK4
SCHEMBL21742661 0.89 L3MBTL1 (0.59) L3MBTL1CYP1A2TSHRCYP2C19CLK4
SCHEMBL12202811 0.89 TSHR (0.68) L3MBTL1CYP1A2TSHRCYP2C19CLK4
SCHEMBL18731953 0.89 L3MBTL1 (0.50) L3MBTL1CYP1A2TSHRCYP2C19CLK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11680071-B2 Compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2023-06-20 US disclosed
EP-3975280-A1 COMPOSITION FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL Chemical & Material Co., Ltd. (JP) 2022-03-30 EP disclosed
US-10910567-B2 Double spiro-type compound and organic light emitting diode comprising same LG CHEM, LTD. 2021-02-02 US disclosed
US-10738034-B2 Spiro compound and organic light-emitting device comprising same LG CHEM, LTD. (KR) 2020-08-11 US disclosed
EP-3345982-B1 DOUBLE SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME LG CHEMICAL LTD (KR) 2020-03-18 EP disclosed
WO-2020009076-A1 POLYCARBONATE RESIN COMPOSITION 帝人株式会社 2020-01-09 WO disclosed
CN-110054593-A Method for synthesizing 1,3, 5-triazine derivative 南京工业大学 2019-07-26 CN disclosed
WO-2019115423-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2019-06-20 WO disclosed
US-10249831-B2 Electronic device containing cyclic lactams MERCK PATENT GMBH (DE) 2019-04-02 US disclosed
US-20180141933-A1 SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-24 US disclosed
US-20180040832-A1 ELECTRONIC DEVICE CONTAINING CYCLIC LACTAMS MERCK PATENT GMBH (DE) 2018-02-08 US disclosed
WO-2018016742-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2018-01-25 WO disclosed
EP-3054498-B1 BISIMIDAZODIAZOCINES IDEMITSU KOSAN CO (JP) 2017-09-20 EP disclosed
US-20170244044-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-08-24 US disclosed
US-20170244044-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-08-24 US disclosed
WO-2017089399-A1 ORGANIC SEMICONDUCTIVE LAYER COMPRISING PHOSPHINE OXIDE COMPOUNDS NOVALED GMBH (DE) 2017-06-01 WO disclosed
WO-2017061810-A1 DOUBLE SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME 주식회사 엘지화학 2017-04-13 WO disclosed
WO-2016128103-A1 ELECTRONIC DEVICE CONTAINING CYCLIC LACTAMS MERCK PATENT GMBH (DE) 2016-08-18 WO disclosed
WO-2016125110-A1 BISIMIDAZOLODIAZOCINES IDEMITSU KOSAN CO., LTD. (JP) 2016-08-11 WO disclosed
EP-3054498-A1 Bisimidazodiazocines Idemitsu Kosan Co., Ltd. (JP) 2016-08-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10738034-B2 Spiro compound and organic light-emitting device comprising same CRY1, NR2E3, ERG L3MBTL1 2838/4885CYP1A2 436/4885TSHR 2800/4885
US-10910567-B2 Double spiro-type compound and organic light emitting diode comprising same NR2E3, ALDH1A2, CRY1 L3MBTL1 2416/4885CYP1A2 264/4885TSHR 2972/4885
US-10249831-B2 Electronic device containing cyclic lactams OXA1L, UROD, MRPL21 L3MBTL1 3138/4885CYP1A2 1135/4885TSHR 4257/4885
US-20180141933-A1 SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CRY1, NR2E3, ERG L3MBTL1 2838/4885CYP1A2 436/4885TSHR 2800/4885
US-20180040832-A1 ELECTRONIC DEVICE CONTAINING CYCLIC LACTAMS OXA1L, UROD, MRPL21 L3MBTL1 3138/4885CYP1A2 1135/4885TSHR 4257/4885
US-11680071-B2 Compound and organic light emitting device comprising the same NCOA4, NR2E3, NCOA1 L3MBTL1 1146/4885CYP1A2 85/4885TSHR 3312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.