Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17965501 | 0.91 | KDM4E (0.44) | KDM4EMAPTHSD17B10POLBLMNA | |
| SCHEMBL19959759 | 0.83 | KDM4E (0.50) | KDM4EMAPTHSD17B10POLBLMNA | |
| SCHEMBL20427381 | 0.82 | KDM4E (0.50) | KDM4EMAPTHSD17B10POLBLMNA | |
| SCHEMBL12719696 | 0.81 | KDM4E (0.53) | KDM4EMAPTHSD17B10POLBLMNA | |
| SCHEMBL21298053 | 0.81 | KDM4E (0.49) | KDM4EMAPTHSD17B10POLBLMNA | |
| SCHEMBL21298050 | 0.81 | KDM4E (0.51) | KDM4EMAPTHSD17B10POLBLMNA | |
| SCHEMBL21298047 | 0.80 | MAPT (0.43) | KDM4EMAPTHSD17B10POLBLMNA | |
| SCHEMBL21298049 | 0.80 | KDM4E (0.42) | KDM4EMAPTHSD17B10POLBLMNA | |
| SCHEMBL10023638 | 0.78 | KDM4E (0.42) | KDM4EMAPTHSD17B10POLBLMNA | |
| SCHEMBL14644245 | 0.78 | KDM4E (0.46) | KDM4EMAPTHSD17B10POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3054498-A1 | Bisimidazodiazocines | Idemitsu Kosan Co., Ltd. (JP) | 2016-08-10 | — | — | EP | disclosed |