SCHEMBL21298047

SCHEMBL21298047

c1ccc2cc3c(cc2c1)c1nc2ccccc2nc1n1c2ccccc2cc31

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.43
KDM4E B2RXH2 6/20 0.43
CASP1 P29466 5/20 0.43
CASP7 P55210 5/20 0.43
MAPK1 P28482 4/20 0.43
L3MBTL1 Q9Y468 4/20 0.43
TSHR P16473 3/20 0.43
HCRTR1 O43613 3/20 0.43
TDP1 Q9NUW8 3/20 0.43
NPC1 O15118 3/20 0.43
HSD17B10 Q99714 3/20 0.43
USP2 O75604 2/20 0.43
ALDH1A1 P00352 2/20 0.43
TP53 P04637 2/20 0.43
ATM Q13315 1/20 0.43
MEN1 O00255 6/20 0.41
KMT2A Q03164 6/20 0.41
POLB P06746 4/20 0.41
LMNA P02545 3/20 0.41
RAB9A P51151 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21298049 0.84 KDM4E (0.42) MAPTKDM4ENPC1HSD17B10ALDH1A1
SCHEMBL21298053 0.82 KDM4E (0.49) MAPTKDM4ECASP1CASP7MAPK1
SCHEMBL21298048 0.82 CTNNB1 (0.30)
SCHEMBL21298363 0.81 MEN1 (0.36) MAPTKDM4ECASP1CASP7MAPK1
SCHEMBL21791036 0.81 MAPT (0.44) MAPTKDM4ECASP1CASP7MAPK1
SCHEMBL17993471 0.80 KDM4E (0.44) MAPTKDM4ECASP1CASP7MAPK1
SCHEMBL21298329 0.80 KDM4E (0.43) MAPTKDM4ECASP1CASP7MAPK1
SCHEMBL19959759 0.80 KDM4E (0.50) MAPTKDM4ECASP1CASP7TSHR
SCHEMBL21298369 0.79 ALDH1A1 (0.32) ALDH1A1
SCHEMBL21298502 0.79 MAPT (0.46) MAPTKDM4ECASP1CASP7MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNIV ARIZONA STATE (US) 2023-06-22 US disclosed
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNIV ARIZONA STATE (US) 2023-06-22 US disclosed
US-20210024526-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNITED STATES DEPARTMENT OF ENERGY 2021-01-28 US disclosed
US-20200071330-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNITED STATES DEPARTMENT OF ENERGY 2020-03-05 US disclosed
US-10392387-B2 Substituted benzo[4,5]imidazo[1,2-a]phenanthro[9,10-c][1,8]naphthyridines, benzo[4,5]imidazo[1,2-a]phenanthro[9,10-c][1,5]naphthyridines and dibenzo[f,h]benzo[4,5]imidazo[2,1-a]pyrazino[2,3-c]isoquinolines as thermally assisted delayed fluorescent materials ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2019-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210024526-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS TTPA, TTC14, AAAS MAPT 467/4885KDM4E 3740/4885CASP1 692/4885
US-20200071330-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS TTPA, TTC14, AAAS MAPT 467/4885KDM4E 3740/4885CASP1 692/4885
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS TTPA, TTC14, AAAS MAPT 467/4885KDM4E 3740/4885CASP1 692/4885
US-10392387-B2 Substituted benzo[4,5]imidazo[1,2-a]phenanthro[9,10-c][1,8]naphthyridines, benzo[4,5]imidazo[1,2-a]phenanthro[9,10-c][1,5]naphthyridines and dibenzo[f,h]benzo[4,5]imidazo[2,1-a]pyrazino[2,3-c]isoquinolines as thermally assisted delayed fluorescent materials NT5C, HTR3D, IK MAPT 2286/4885KDM4E 2046/4885CASP1 307/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.