SCHEMBL21298049

SCHEMBL21298049

c1ccc2cc3c(cc2c1)c1cc2ccccc2nc1n1c2ccccc2cc31

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.42
RXFP1 Q9HBX9 1/20 0.42
MAPT P10636 5/20 0.41
LMNA P02545 3/20 0.41
POLB P06746 2/20 0.41
TP53 P04637 2/20 0.41
HSD17B10 Q99714 1/20 0.41
HPGD P15428 7/20 0.40
ALDH1A1 P00352 7/20 0.40
GLA P06280 2/20 0.39
ACHE P22303 1/20 0.39
KMT2A Q03164 5/20 0.38
MEN1 O00255 2/20 0.38
GAA P10253 2/20 0.38
NPC1 O15118 2/20 0.38
PTBP1 P26599 1/20 0.38
RAB9A P51151 1/20 0.38
RCE1 Q9Y256 1/20 0.38
TERT O14746 1/20 0.36
ESR1 P03372 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19959759 0.90 KDM4E (0.50) KDM4EMAPTLMNAPOLBTP53
SCHEMBL21298050 0.85 KDM4E (0.51) KDM4ERXFP1MAPTLMNAPOLB
SCHEMBL21298047 0.84 MAPT (0.43) KDM4EMAPTLMNAPOLBTP53
SCHEMBL12719696 0.82 KDM4E (0.53) KDM4EMAPTLMNAPOLBTP53
SCHEMBL21298505 0.81 KDM4E (0.39) KDM4ERXFP1MAPTLMNAPOLB
SCHEMBL21791146 0.81 KDM4E (0.39) KDM4ERXFP1MAPTLMNAPOLB
SCHEMBL21298046 0.80 CDC25B (0.36) KDM4EMAPTLMNAHSD17B10HPGD
SCHEMBL10023597 0.80 KDM4E (0.47) KDM4ERXFP1MAPTLMNAPOLB
SCHEMBL21298328 0.80 KDM4E (0.41) KDM4ERXFP1MAPTLMNAPOLB
SCHEMBL17993471 0.80 KDM4E (0.44) KDM4ERXFP1MAPTLMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNIV ARIZONA STATE (US) 2023-06-22 US disclosed
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNIV ARIZONA STATE (US) 2023-06-22 US disclosed
US-20210024526-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNITED STATES DEPARTMENT OF ENERGY 2021-01-28 US disclosed
US-20200071330-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNITED STATES DEPARTMENT OF ENERGY 2020-03-05 US disclosed
US-10392387-B2 Substituted benzo[4,5]imidazo[1,2-a]phenanthro[9,10-c][1,8]naphthyridines, benzo[4,5]imidazo[1,2-a]phenanthro[9,10-c][1,5]naphthyridines and dibenzo[f,h]benzo[4,5]imidazo[2,1-a]pyrazino[2,3-c]isoquinolines as thermally assisted delayed fluorescent materials ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2019-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210024526-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS TTPA, TTC14, AAAS KDM4E 3740/4885RXFP1 4556/4885MAPT 467/4885
US-20200071330-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS TTPA, TTC14, AAAS KDM4E 3740/4885RXFP1 4556/4885MAPT 467/4885
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS TTPA, TTC14, AAAS KDM4E 3740/4885RXFP1 4556/4885MAPT 467/4885
US-10392387-B2 Substituted benzo[4,5]imidazo[1,2-a]phenanthro[9,10-c][1,8]naphthyridines, benzo[4,5]imidazo[1,2-a]phenanthro[9,10-c][1,5]naphthyridines and dibenzo[f,h]benzo[4,5]imidazo[2,1-a]pyrazino[2,3-c]isoquinolines as thermally assisted delayed fluorescent materials NT5C, HTR3D, IK KDM4E 2046/4885RXFP1 4648/4885MAPT 2286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.