Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.44 |
| ▸ | FAAH | O00519 | 3/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | NAT1 | P18440 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1908629 | 0.75 | MGLL (0.64) | MGLLFAAHPTPN1 | |
| SCHEMBL598742 | 0.75 | MGLL (0.64) | MGLLFAAHPTPN1 | |
| SCHEMBL21993642 | 0.62 | MGLL (1.00) | MGLLFAAHALDH1A1HSP90AA1PKM | |
| SCHEMBL9719419 | 0.62 | MGLL (1.00) | MGLLFAAHALDH1A1HSP90AA1PKM | |
| SCHEMBL9261050 | 0.62 | SIRT2 (0.42) | SIRT2SIRT1SIRT3SIRT5TP53 | |
| SCHEMBL20299501 | 0.62 | LCK (0.56) | SIRT2SIRT1SIRT3SIRT5PTPN1 | |
| SCHEMBL716487 | 0.61 | — | — | |
| SCHEMBL13514984 | 0.60 | ALDH1A1 (0.50) | MGLLSIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL10969109 | 0.60 | ALDH1A1 (0.68) | MGLLTP53ALDH1A1LMNAMAPT | |
| SCHEMBL6032 | 0.60 | ALDH1A1 (0.68) | MGLLTP53ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121578-B1 | PROCESS FOR PREPARING 5-BIPHENYL-4-AMINO-2-METHYL PENTANOIC ACID | NOVARTIS AG (CH) | 2016-08-10 | — | — | EP | disclosed |