SCHEMBL179939

SCHEMBL179939

CC(C)CC1=Cc2c(cc3c(c2Br)CCC3)C1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NLRP3 Q96P20 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2965987 0.81 GNG2 (0.32)
SCHEMBL179888 0.80
SCHEMBL6055942 0.78
SCHEMBL29596207 0.75 MAPT (0.33) NLRP3
SCHEMBL18281521 0.75 MAPT (0.33) NLRP3
SCHEMBL2960447 0.72 MEN1 (0.31)
SCHEMBL19475118 0.68 NLRP3 (0.38) NLRP3
SCHEMBL30042078 0.64 NLRP3 (0.36) NLRP3
SCHEMBL28228485 0.64 TSHR (0.35) NLRP3
SCHEMBL20915339 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2402353-B1 Group 4 metallocenes useful as catalysts for the polymerization of olefins BOREALIS AG (AT) 2018-04-25 EP disclosed
EP-2402354-B1 Process for olefin polymerisation using group 4 metallocene as catalysts BOREALIS AG (AT) 2016-03-02 EP disclosed
US-8933256-B2 Catalysts BOREALIS AG (AT) 2015-01-13 US disclosed
US-8865848-B2 Process for olefin polymerisation using group 4 metallocene as catalysts BOREALIS AG (AT) 2014-10-21 US disclosed
US-20130289229-A1 CATALYSTS BOREALIS AG (AT) 2013-10-31 US disclosed
US-20130217845-A1 PROCESS FOR OLEFIN POLYMERISATION USING GROUP 4 METALLOCENE AS CATALYSTS BOREALIS AG (AT) 2013-08-22 US disclosed
EP-2402353-A1 Group 4 metallocenes useful as catalysts for the polymerization of olefins Borealis AG (AT) 2012-01-04 EP disclosed
EP-2402354-A1 Process for olefin polymerisation using group 4 metallocene as catalysts Borealis AG (AT) 2012-01-04 EP disclosed