⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2963075 | 0.81 | GNG2 (0.32) | — | |
| SCHEMBL179939 | 0.80 | NLRP3 (0.30) | — | |
| SCHEMBL2972387 | 0.79 | — | — | |
| SCHEMBL10053650 | 0.75 | — | — | |
| SCHEMBL179984 | 0.75 | ACHE (0.33) | — | |
| SCHEMBL180041 | 0.74 | FGF23 (0.31) | — | |
| SCHEMBL2961701 | 0.72 | MEN1 (0.31) | — | |
| SCHEMBL19475118 | 0.68 | NLRP3 (0.38) | — | |
| SCHEMBL30042078 | 0.64 | NLRP3 (0.36) | — | |
| SCHEMBL28228485 | 0.64 | TSHR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402353-B1 | Group 4 metallocenes useful as catalysts for the polymerization of olefins | BOREALIS AG (AT) | 2018-04-25 | — | — | EP | disclosed |
| EP-2402353-B1 | Group 4 metallocenes useful as catalysts for the polymerization of olefins | BOREALIS AG (AT) | 2018-04-25 | — | — | EP | disclosed |
| EP-2402354-B1 | Process for olefin polymerisation using group 4 metallocene as catalysts | BOREALIS AG (AT) | 2016-03-02 | — | — | EP | disclosed |
| EP-2402354-B1 | Process for olefin polymerisation using group 4 metallocene as catalysts | BOREALIS AG (AT) | 2016-03-02 | — | — | EP | disclosed |
| US-8933256-B2 | Catalysts | BOREALIS AG (AT) | 2015-01-13 | — | — | US | disclosed |
| US-8933256-B2 | Catalysts | BOREALIS AG (AT) | 2015-01-13 | — | — | US | disclosed |
| US-8933256-B2 | Catalysts | BOREALIS AG (AT) | 2015-01-13 | — | — | US | disclosed |
| US-8865848-B2 | Process for olefin polymerisation using group 4 metallocene as catalysts | BOREALIS AG (AT) | 2014-10-21 | — | — | US | disclosed |
| US-8865848-B2 | Process for olefin polymerisation using group 4 metallocene as catalysts | BOREALIS AG (AT) | 2014-10-21 | — | — | US | disclosed |
| US-8865848-B2 | Process for olefin polymerisation using group 4 metallocene as catalysts | BOREALIS AG (AT) | 2014-10-21 | — | — | US | disclosed |
| US-20130289229-A1 | CATALYSTS | BOREALIS AG (AT) | 2013-10-31 | — | — | US | disclosed |
| US-20130217845-A1 | PROCESS FOR OLEFIN POLYMERISATION USING GROUP 4 METALLOCENE AS CATALYSTS | BOREALIS AG (AT) | 2013-08-22 | — | — | US | disclosed |
| US-20130217845-A1 | PROCESS FOR OLEFIN POLYMERISATION USING GROUP 4 METALLOCENE AS CATALYSTS | BOREALIS AG (AT) | 2013-08-22 | — | — | US | disclosed |
| US-20130217845-A1 | PROCESS FOR OLEFIN POLYMERISATION USING GROUP 4 METALLOCENE AS CATALYSTS | BOREALIS AG (AT) | 2013-08-22 | — | — | US | disclosed |
| WO-2012001051-A1 | PROCESS FOR OLEFIN POLYMERISATION USING GROUP 4 METALLOCENE AS CATALYSTS | BOREALIS AG (AT) | 2012-01-05 | — | — | WO | disclosed |
| WO-2012001052-A2 | CATALYSTS | BOREALIS AG (AT) | 2012-01-05 | — | — | WO | disclosed |
| EP-2402353-A1 | Group 4 metallocenes useful as catalysts for the polymerization of olefins | Borealis AG (AT) | 2012-01-04 | — | — | EP | disclosed |
| EP-2402353-A1 | Group 4 metallocenes useful as catalysts for the polymerization of olefins | Borealis AG (AT) | 2012-01-04 | — | — | EP | disclosed |
| EP-2402354-A1 | Process for olefin polymerisation using group 4 metallocene as catalysts | Borealis AG (AT) | 2012-01-04 | — | — | EP | disclosed |
| EP-2402354-A1 | Process for olefin polymerisation using group 4 metallocene as catalysts | Borealis AG (AT) | 2012-01-04 | — | — | EP | disclosed |